Forecast of dementia prevalence in Germany and subnational regions until 2060 using microsimulation.

IF 5.9 1区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Katrin Schüssel, Gabriela Brückner, Helmut Schröder, Gabriele Doblhammer, Frank Jessen, Julian Ernst, Christopher Caratiola, Ralf Münnich
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引用次数: 0

Abstract

The number of dementia cases is expected to rise in ageing societies with concomitant requirements for healthcare planning. While national figures for countries are widely available, subnational regional heterogeneity is rarely considered. This study aimed at projecting national and subnational dementia figures under different scenarios. Dementia and population figures where projected from 2018 to 2060 by microsimulation at the level of 400 counties within Germany. The German MikroSim model was supplemented with dementia-specific data on regional prevalence and national incidence and mortality figures. These data were derived from routine health insurance records of 27 million individuals within the AOK fund during pre-pandemic years 2017 to 2019 and adjusted to the total population of 2018. Scenarios with increasing life expectancy or prevention effects (decreasing dementia incidence by 1 to 2% per year) were calculated. Increasing life expectancy leads to dementia cases rising from 1.4 million in 2018 to 2.1 million in 2060, prevalence from 1.6 to 2.6% and the RWA (ratio of cases per 100 individuals of working age) from 2.6 to 4.7. In prevention scenarios, these figures are substantially lower: between 1.3 and 1.5 million cases, 1.6 and 1.9% prevalence and RWA between 2.9 and 3.4. Existing subnational regional differences in prevalence and RWA will become more pronounced in all scenarios. Growing life expectancy leads to an increase in dementia cases, which may be counteracted by preventive measures. Increasing regional heterogeneity in prevalence and RWA should be considered for health care planning.

使用微观模拟预测2060年前德国和国家以下地区的痴呆患病率。
在老龄化社会中,痴呆症病例的数量预计会增加,同时对医疗保健计划也有要求。虽然各国的国家数据可以广泛获得,但很少考虑到国家以下区域的异质性。这项研究旨在预测不同情景下的国家和地方痴呆症数字。通过微观模拟,预测了2018年至2060年德国400个县的痴呆症和人口数据。德国的MikroSim模型补充了关于区域患病率和国家发病率和死亡率的痴呆症特定数据。这些数据来自2017年至2019年大流行前期间AOK基金内2700万人的常规健康保险记录,并根据2018年的总人口进行了调整。计算了预期寿命增加或预防效果(每年减少痴呆症发病率1%至2%)的情景。预期寿命的延长导致痴呆症病例从2018年的140万例增加到2060年的210万例,患病率从1.6%增加到2.6%,RWA(每100名工作年龄人口的病例比率)从2.6增加到4.7。在预防情景中,这些数字要低得多:130万至150万病例,患病率为1.6%至1.9%,RWA为2.9至3.4。在所有情况下,现有的次国家区域流行率和近东救济工程处的差异将变得更加明显。预期寿命的延长导致痴呆症病例的增加,这可以通过预防措施加以抵消。卫生保健规划应考虑到患病率和RWA的区域异质性日益增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
European Journal of Epidemiology
European Journal of Epidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
21.40
自引率
1.50%
发文量
109
审稿时长
6-12 weeks
期刊介绍: The European Journal of Epidemiology, established in 1985, is a peer-reviewed publication that provides a platform for discussions on epidemiology in its broadest sense. It covers various aspects of epidemiologic research and statistical methods. The journal facilitates communication between researchers, educators, and practitioners in epidemiology, including those in clinical and community medicine. Contributions from diverse fields such as public health, preventive medicine, clinical medicine, health economics, and computational biology and data science, in relation to health and disease, are encouraged. While accepting submissions from all over the world, the journal particularly emphasizes European topics relevant to epidemiology. The published articles consist of empirical research findings, developments in methodology, and opinion pieces.
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