Katrin Schüssel, Gabriela Brückner, Helmut Schröder, Gabriele Doblhammer, Frank Jessen, Julian Ernst, Christopher Caratiola, Ralf Münnich
{"title":"Forecast of dementia prevalence in Germany and subnational regions until 2060 using microsimulation.","authors":"Katrin Schüssel, Gabriela Brückner, Helmut Schröder, Gabriele Doblhammer, Frank Jessen, Julian Ernst, Christopher Caratiola, Ralf Münnich","doi":"10.1007/s10654-026-01392-4","DOIUrl":null,"url":null,"abstract":"<p><p>The number of dementia cases is expected to rise in ageing societies with concomitant requirements for healthcare planning. While national figures for countries are widely available, subnational regional heterogeneity is rarely considered. This study aimed at projecting national and subnational dementia figures under different scenarios. Dementia and population figures where projected from 2018 to 2060 by microsimulation at the level of 400 counties within Germany. The German MikroSim model was supplemented with dementia-specific data on regional prevalence and national incidence and mortality figures. These data were derived from routine health insurance records of 27 million individuals within the AOK fund during pre-pandemic years 2017 to 2019 and adjusted to the total population of 2018. Scenarios with increasing life expectancy or prevention effects (decreasing dementia incidence by 1 to 2% per year) were calculated. Increasing life expectancy leads to dementia cases rising from 1.4 million in 2018 to 2.1 million in 2060, prevalence from 1.6 to 2.6% and the RWA (ratio of cases per 100 individuals of working age) from 2.6 to 4.7. In prevention scenarios, these figures are substantially lower: between 1.3 and 1.5 million cases, 1.6 and 1.9% prevalence and RWA between 2.9 and 3.4. Existing subnational regional differences in prevalence and RWA will become more pronounced in all scenarios. Growing life expectancy leads to an increase in dementia cases, which may be counteracted by preventive measures. Increasing regional heterogeneity in prevalence and RWA should be considered for health care planning.</p>","PeriodicalId":11907,"journal":{"name":"European Journal of Epidemiology","volume":" ","pages":""},"PeriodicalIF":5.9000,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Epidemiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10654-026-01392-4","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
The number of dementia cases is expected to rise in ageing societies with concomitant requirements for healthcare planning. While national figures for countries are widely available, subnational regional heterogeneity is rarely considered. This study aimed at projecting national and subnational dementia figures under different scenarios. Dementia and population figures where projected from 2018 to 2060 by microsimulation at the level of 400 counties within Germany. The German MikroSim model was supplemented with dementia-specific data on regional prevalence and national incidence and mortality figures. These data were derived from routine health insurance records of 27 million individuals within the AOK fund during pre-pandemic years 2017 to 2019 and adjusted to the total population of 2018. Scenarios with increasing life expectancy or prevention effects (decreasing dementia incidence by 1 to 2% per year) were calculated. Increasing life expectancy leads to dementia cases rising from 1.4 million in 2018 to 2.1 million in 2060, prevalence from 1.6 to 2.6% and the RWA (ratio of cases per 100 individuals of working age) from 2.6 to 4.7. In prevention scenarios, these figures are substantially lower: between 1.3 and 1.5 million cases, 1.6 and 1.9% prevalence and RWA between 2.9 and 3.4. Existing subnational regional differences in prevalence and RWA will become more pronounced in all scenarios. Growing life expectancy leads to an increase in dementia cases, which may be counteracted by preventive measures. Increasing regional heterogeneity in prevalence and RWA should be considered for health care planning.
期刊介绍:
The European Journal of Epidemiology, established in 1985, is a peer-reviewed publication that provides a platform for discussions on epidemiology in its broadest sense. It covers various aspects of epidemiologic research and statistical methods. The journal facilitates communication between researchers, educators, and practitioners in epidemiology, including those in clinical and community medicine. Contributions from diverse fields such as public health, preventive medicine, clinical medicine, health economics, and computational biology and data science, in relation to health and disease, are encouraged. While accepting submissions from all over the world, the journal particularly emphasizes European topics relevant to epidemiology. The published articles consist of empirical research findings, developments in methodology, and opinion pieces.