Burn depth assessment by photoacoustic imaging: A review

IF 4.3 3区生物学 Q1 BIOCHEMICAL RESEARCH METHODS

Methods Pub Date : 2026-08-01 Epub Date: 2026-04-30 DOI:10.1016/j.ymeth.2026.04.014

Jiachen Zhou , Siqi Liang , Jeong Hyeon Park , Anh Nguyen , Myeongsu Seong

引用次数: 0

Abstract

Accurate and timely assessment of burn depth is critical for determining effective treatment strategies and improving patient outcomes. However, traditional diagnostic methods, such as visual inspection and histological analysis, are constrained by subjectivity, invasiveness, and diagnostic delays. Photoacoustic imaging (PAI), a hybrid modality combining optical contrast with ultrasonic resolution, has emerged as a promising tool for biomedical applications due to its high sensitivity to endogenous chromophores and capability for depth-resolved functional imaging. Although various PAI configurations have been investigated for non-invasive burn assessment, a comprehensive synthesis of this specific application is currently lacking. To address this gap, this review provides a detailed overview of the fundamental principles of PAI, evaluates its distinct advantages in burn depth assessment, and discusses current technological advancements, translational challenges, and future perspectives.

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光声成像评价烧伤深度的研究进展。

准确及时地评估烧伤深度对于确定有效的治疗策略和改善患者预后至关重要。然而，传统的诊断方法，如视觉检查和组织学分析，受到主观性、侵入性和诊断延迟的限制。光声成像（PAI）是一种结合光学对比度和超声分辨率的混合成像技术，由于其对内源性发色团的高灵敏度和深度分辨率的功能成像能力，已成为生物医学应用的一种有前途的工具。尽管已经研究了各种PAI配置用于无创烧伤评估，但目前缺乏对这一特定应用的全面综合。为了解决这一差距，本文详细概述了PAI的基本原理，评估了其在烧伤深度评估方面的独特优势，并讨论了当前的技术进步、转化挑战和未来前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Methods 生物-生化研究方法

CiteScore

9.80

自引率

2.10%

发文量

222

审稿时长

11.3 weeks

期刊介绍： Methods focuses on rapidly developing techniques in the experimental biological and medical sciences. Each topical issue, organized by a guest editor who is an expert in the area covered, consists solely of invited quality articles by specialist authors, many of them reviews. Issues are devoted to specific technical approaches with emphasis on clear detailed descriptions of protocols that allow them to be reproduced easily. The background information provided enables researchers to understand the principles underlying the methods; other helpful sections include comparisons of alternative methods giving the advantages and disadvantages of particular methods, guidance on avoiding potential pitfalls, and suggestions for troubleshooting.