Highlights of 2025: epithelial-immune circuitry in allergic airway inflammation

IF 3.3 4区医学 Q3 CELL BIOLOGY

Immunology & Cell Biology Pub Date : 2026-07-03 Epub Date: 2026-05-04 DOI:10.1111/imcb.70126

Rebecca Palmer, Olivier Lamiable, Kerry L. Hilligan

引用次数: 0

Abstract

In this Highlights article, allergic asthma and rhinitis are reframed as diseases of epithelial-immune dysregulation. Advances from 2025 establish epithelial-immune circuitry as a central organizing principle of allergic airway inflammation—spanning allergen sensing, memory T-cell function and perpetuation of inflammatory niches—and provide a foundation for next-generation, tissue-directed therapies.

Abstract Image

查看原文本刊更多论文

2025年的亮点：过敏性气道炎症的上皮免疫回路。

在这篇重点文章中，过敏性哮喘和鼻炎被重新定义为上皮免疫失调的疾病。2025年以来的进展确立了上皮免疫回路作为过敏性气道炎症的中心组织原则——跨越过敏原感知、记忆t细胞功能和炎症龛的延续——并为下一代组织导向治疗提供了基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Immunology & Cell Biology 医学-免疫学

CiteScore

7.50

自引率

2.50%

发文量

审稿时长

4-8 weeks

期刊介绍： The Australasian Society for Immunology Incorporated (ASI) was created by the amalgamation in 1991 of the Australian Society for Immunology, formed in 1970, and the New Zealand Society for Immunology, formed in 1975. The aim of the Society is to encourage and support the discipline of immunology in the Australasian region. It is a broadly based Society, embracing clinical and experimental, cellular and molecular immunology in humans and animals. The Society provides a network for the exchange of information and for collaboration within Australia, New Zealand and overseas. ASI members have been prominent in advancing biological and medical research worldwide. We seek to encourage the study of immunology in Australia and New Zealand and are active in introducing young scientists to the discipline.