Valoración del flujo sanguíneo miocárdico absoluto con una gammacámara cardiodedicada de detectores CZT: metodología y descripción de posibles artefactos

IF 1.6 4区医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2026-05-01 Epub Date: 2025-12-22 DOI:10.1016/j.remn.2025.500271

A. Palomar-Muñoz , A. Cardozo-Saavedra , M.J. Díez-Castro , M.C. López Arribas , M.N. Pizzi , A. Roque-Pérez , S. Aguadé-Bruix , D. Sánchez-Artuñedo , C. Gámez-Cenzano

{"title":"Valoración del flujo sanguíneo miocárdico absoluto con una gammacámara cardiodedicada de detectores CZT: metodología y descripción de posibles artefactos","authors":"A. Palomar-Muñoz , A. Cardozo-Saavedra , M.J. Díez-Castro , M.C. López Arribas , M.N. Pizzi , A. Roque-Pérez , S. Aguadé-Bruix , D. Sánchez-Artuñedo , C. Gámez-Cenzano","doi":"10.1016/j.remn.2025.500271","DOIUrl":null,"url":null,"abstract":"<div><div>Non-invasive techniques for assessing myocardial perfusion provide key functional information for the diagnosis of coronary artery disease and risk stratification in ischaemic heart disease. However, despite their adequate diagnostic performance, relative myocardial perfusion images have limitations in detecting ischaemia balanced by multivessel disease and in evaluating microvascular disease. The assessment of myocardial blood flow (MBF) and myocardial flow reserve (MFR) may be useful in cases where the technique is limited by balanced disease or in patients with healthy coronary arteries and suspected microvascular involvement.</div><div>The introduction of new-generation gamma cameras with cadmium-zinc-tellurium (CZT) detectors allows, due to their higher spatial and energy resolution and greater sensitivity than conventional equipment, the isotopic assessment of microvascular disease using SPECT, which until recently was mainly evaluated using the goldstandard technique, positron emission tomography (PET).</div><div>The aim of this collaborative article is to describe the protocol developed at the Nuclear Medicine Service of Vall d’Hebron Hospital for quantifying MBF using a dedicated cardiac gamma camera (MyoSPECTTM, GE HealthCare), emphasising the particularities of image acquisition and post-processing, as well as possible artefacts.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"45 3","pages":"Article 500271"},"PeriodicalIF":1.6000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espanola De Medicina Nuclear E Imagen Molecular","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2253654X25001714","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/12/22 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

Abstract

Non-invasive techniques for assessing myocardial perfusion provide key functional information for the diagnosis of coronary artery disease and risk stratification in ischaemic heart disease. However, despite their adequate diagnostic performance, relative myocardial perfusion images have limitations in detecting ischaemia balanced by multivessel disease and in evaluating microvascular disease. The assessment of myocardial blood flow (MBF) and myocardial flow reserve (MFR) may be useful in cases where the technique is limited by balanced disease or in patients with healthy coronary arteries and suspected microvascular involvement.

The introduction of new-generation gamma cameras with cadmium-zinc-tellurium (CZT) detectors allows, due to their higher spatial and energy resolution and greater sensitivity than conventional equipment, the isotopic assessment of microvascular disease using SPECT, which until recently was mainly evaluated using the goldstandard technique, positron emission tomography (PET).

The aim of this collaborative article is to describe the protocol developed at the Nuclear Medicine Service of Vall d’Hebron Hospital for quantifying MBF using a dedicated cardiac gamma camera (MyoSPECTTM, GE HealthCare), emphasising the particularities of image acquisition and post-processing, as well as possible artefacts.

查看原文本刊更多论文

用CZT专用心电图仪测量绝对心血流量：方法和可能的装置说明

无创心肌灌注评估技术为缺血性心脏病的冠状动脉疾病诊断和危险分层提供了关键的功能信息。然而，尽管相对心肌灌注图像具有足够的诊断性能，但在检测多血管疾病平衡的缺血和评估微血管疾病方面存在局限性。心肌血流（MBF）和心肌血流储备（MFR）的评估可能在该技术受到平衡疾病限制的情况下或在健康冠状动脉和怀疑微血管受累的患者中有用。与传统设备相比，新一代带有镉锌碲（CZT）探测器的伽马相机具有更高的空间和能量分辨率以及更高的灵敏度，因此可以使用SPECT进行微血管疾病的同位素评估，直到最近主要使用金标准技术，正电子发射断层扫描（PET）进行评估。这篇合作文章的目的是描述Vall d 'Hebron医院核医学服务部开发的使用专用心脏伽马相机（MyoSPECTTM, GE HealthCare）量化MBF的方案，强调图像采集和后处理的特殊性，以及可能的伪像。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista Espanola De Medicina Nuclear E Imagen Molecular RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.10

自引率

16.70%

发文量

审稿时长

24 days

期刊介绍： The Revista Española de Medicina Nuclear e Imagen Molecular (Spanish Journal of Nuclear Medicine and Molecular Imaging), was founded in 1982, and is the official journal of the Spanish Society of Nuclear Medicine and Molecular Imaging, which has more than 700 members. The Journal, which publishes 6 regular issues per year, has the promotion of research and continuing education in all fields of Nuclear Medicine as its main aim. For this, its principal sections are Originals, Clinical Notes, Images of Interest, and Special Collaboration articles.