Association between oral frailty and a laboratory-based frailty index in older adults.

IF 3.6 3区医学 Q2 GERIATRICS & GERONTOLOGY

European Geriatric Medicine Pub Date : 2026-04-27 DOI:10.1007/s41999-026-01489-9

Shuzo Miyahara, Keisuke Maeda, Koki Kawamura, Shosuke Satake, Hiroyasu Akatsu, Hidenori Arai

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引用次数: 0

Abstract

Purpose: To examine the association between oral frailty and laboratory-based Frailty Index (FI-lab) in older adults.

Methods: This cross-sectional study included patients aged ≥ 65 years who attended a frailty outpatient clinic. Oral frailty was assessed using the Oral Frailty five-item checklist. The FI-lab was constructed from 31 laboratory parameters, with frailty defined as an FI-lab value > 0.21. The association between oral frailty and FI-lab-defined frailty was examined using multivariable logistic regression analysis.

Results: Among the 486 patients, the mean age was 77.9 ± 6.3 years, and 63.6% were women. The prevalence of oral frailty was 49.6%, and the median FI-lab value was 0.16. Oral frailty was significantly associated with FI-lab-defined frailty after adjustment for age, sex, and comorbidities (odds ratio 1.52, 95% confidence interval 1.01-2.29).

Conclusion: Oral frailty is associated with FI-lab-defined frailty, suggesting a relationship between oral function and latent physiological vulnerability, as captured by the FI-lab.

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老年人口腔虚弱和实验室虚弱指数之间的关系。

目的：探讨老年人口腔虚弱与实验室虚弱指数（FI-lab）之间的关系。方法：这项横断面研究纳入了年龄≥65岁、在虚弱门诊就诊的患者。使用口腔虚弱五项检查表评估口腔虚弱。FI-lab由31个实验室参数构建，定义脆弱性为FI-lab值> 0.21。使用多变量logistic回归分析检验口腔虚弱与fi实验室定义的虚弱之间的关系。结果：486例患者平均年龄77.9±6.3岁，女性占63.6%。口腔虚弱的患病率为49.6%，FI-lab中位值为0.16。在调整年龄、性别和合并症后，口腔虚弱与fi实验室定义的虚弱显著相关（优势比1.52,95%可信区间1.01-2.29）。结论：口腔脆弱与FI-lab定义的脆弱相关，表明口腔功能与潜在的生理脆弱性之间存在关系，正如FI-lab所捕获的那样。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Geriatric Medicine GERIATRICS & GERONTOLOGY-

CiteScore

6.70

自引率

2.60%

发文量

114

审稿时长

6-12 weeks

期刊介绍： European Geriatric Medicine is the official journal of the European Geriatric Medicine Society (EUGMS). Launched in 2010, this journal aims to publish the highest quality material, both scientific and clinical, on all aspects of Geriatric Medicine. The EUGMS is interested in the promotion of Geriatric Medicine in any setting (acute or subacute care, rehabilitation, nursing homes, primary care, fall clinics, ambulatory assessment, dementia clinics..), and also in functionality in old age, comprehensive geriatric assessment, geriatric syndromes, geriatric education, old age psychiatry, models of geriatric care in health services, and quality assurance.