Variations in Eclampsia Risk Across Asian Origin Groups in the United States.

IF 1.7 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Maternal and Child Health Journal Pub Date : 2026-04-29 DOI:10.1007/s10995-026-04261-4

Weisi Huang, Guohua Li, Alexander Friedman, Jean Guglielminotti

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引用次数: 0

Abstract

Objectives: Eclampsia is a leading contributor of severe maternal morbidity in the United States. Although the rates of severe maternal morbidity for Asian and non-Hispanic White birthing people are similar, variations in eclampsia risk across Asian origin groups have not been adequately studied.

Methods: A cross-sectional study using public access Natality Files data (2018-2021). The exposure was maternal race (non-Hispanic White or Asian), and nativity (foreign- or US-born), with foreign-born non-Hispanic White birthing people defined as the reference group. The outcome was eclampsia. Adjusted odds ratios (aOR) and 95% confidence intervals (CI) of eclampsia associated with race and nativity were estimated using multivariable logistic regression models.

Results: Of the 8,295,025 birth certificates analyzed, 21,547 (26.0 per 10,000) recorded eclampsia. The incidence of eclampsia per 10,000 was 14.7 for foreign-born White people, 26.7 for US-born White, 20.9 for foreign-born Asians, and 49.6 for US-born Asians. Among Asian origin groups, the highest incidence of eclampsia per 10,000 was observed among US-born Japanese (256.0), followed by US-born Filipinos (120.6), foreign-born Filipinos (82.9) and US-born Japanese (32.7). After adjustment and compared to foreign-born White people, US-born Filipinos had the highest odds of eclampsia (aOR: 9.36; 95% CI: 7.51, 11.67), followed by foreign-born Filipino (aOR: 6.09; 95% CI: 4.95, 7.50), US-born Japanese (aOR: 4.89; 95% CI: 3.45, 6.92), foreign-born Japanese (aOR: 3.18; 95% CI:2.26, 4.47), and US-born non-Hispanic White (aOR: 2.13; 95% CI: 1.96, 2.32).

Conclusions for practice: Eclampsia risk varies significantly across Asian origin groups and by nativity.

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美国亚裔人群子痫风险的差异

目的：子痫是在美国严重的产妇发病率的主要贡献者。尽管亚裔和非西班牙裔白人孕妇的严重产妇发病率相似，但亚裔人群子痫风险的差异尚未得到充分研究。方法：使用公共访问出生文件数据（2018-2021）进行横断面研究。暴露是母亲的种族（非西班牙裔白人或亚洲人）和出生（外国或美国出生），外国出生的非西班牙裔白人出生的人被定义为参照组。结果是子痫。使用多变量logistic回归模型估计子痫与种族和出生相关的校正优势比（aOR）和95%置信区间（CI）。结果：在8,295,025份出生证明中，21,547份（26.0 / 10,000）记录了子痫。外国出生的白人的子痫发病率为14.7 / 10000，美国出生的白人为26.7 / 10000，外国出生的亚洲人为20.9 / 10000，美国出生的亚洲人为49.6 / 10000。在亚裔人群中，美国出生的日本人的子痫发病率最高（每万人256.0例），其次是美国出生的菲律宾人（120.6例），外国出生的菲律宾人（82.9例）和美国出生的日本人（32.7例）。调整后，与外国出生的白人相比，美国出生的菲律宾人患子痫的几率最高（aOR: 9.36; 95% CI: 7.51, 11.67），其次是外国出生的菲律宾人（aOR: 6.09; 95% CI: 4.95, 7.50），美国出生的日本人（aOR: 4.89; 95% CI: 3.45, 6.92），外国出生的日本人（aOR: 3.18; 95% CI:2.26, 4.47）和美国出生的非西班牙裔白人（aOR: 2.13; 95% CI: 1.96, 2.32）。实践结论：子痫的风险在不同的亚裔群体和出生地有显著差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Maternal and Child Health Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.20

自引率

4.30%

发文量

271

期刊介绍： Maternal and Child Health Journal is the first exclusive forum to advance the scientific and professional knowledge base of the maternal and child health (MCH) field. This bimonthly provides peer-reviewed papers addressing the following areas of MCH practice, policy, and research: MCH epidemiology, demography, and health status assessment Innovative MCH service initiatives Implementation of MCH programs MCH policy analysis and advocacy MCH professional development. Exploring the full spectrum of the MCH field, Maternal and Child Health Journal is an important tool for practitioners as well as academics in public health, obstetrics, gynecology, prenatal medicine, pediatrics, and neonatology. Sponsors include the Association of Maternal and Child Health Programs (AMCHP), the Association of Teachers of Maternal and Child Health (ATMCH), and CityMatCH.