Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology

IF 3.2 2区 心理学 Q1 PSYCHIATRY
European Eating Disorders Review Pub Date : 2026-08-03 Epub Date: 2026-04-26 DOI:10.1002/erv.70122
Mariana Valdez Aguilar, Gabriela K. Giulumian, Isabel Rodriguez, Jessica H. Baker, Preina P. Surti, Lisa Dinkler, Jerry Guintivano, Jessica S. Johnson, Casey M. MacDermod, Shelby N. Ortiz, Emily M. Pisetsky, Jennifer P. White, Nadia Micali, Cynthia M. Bulik, Laura M. Thornton, Ya-Ke Wu
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引用次数: 0

Abstract

Objective

Although obsessive-compulsive disorder (OCD) commonly co-occurs with anorexia nervosa and bulimia nervosa, less is known about its relationship with avoidant/restrictive food intake disorder (ARFID) dimensions. Whether associations between ARFID dimensions and OCD differ by sex is also unclear. We examined associations between ARFID dimensions and OCD symptoms by sex, accounting for depression and anxiety.

Methods

Data from 3120 participants ages 15+ in the ARFID Genes and Environment (ARFID-GEN) study were analyzed. ARFID dimensions (i.e., sensory sensitivity; low appetite/lack of interest in food; and fear of aversive consequences), OCD symptoms, anxiety, and depression were assessed using validated self-report measures. We evaluated associations between ARFID dimensions and OCD symptoms using general linear models, adjusting for depression and anxiety.

Results

ARFID dimensions were significantly associated with OCD symptoms. After adjusting for depression and anxiety, these associations were attenuated but remained significant for all ARFID dimensions. Associations between ARFID dimensions and OCD symptoms varied by sex.

Conclusion

The relation between ARFID symptomatology and OCD warrants further exploration across the developmental spectrum in which ARFID appears. Clinically, bidirectional screening may improve diagnostic clarity and be informative to tailor interventions appropriately.

Trial Registration

ARFID-GEN is registered in clinicaltrials.gov (NCT05605067)

回避/限制性食物摄入障碍维度与强迫症症状之间的关系。
目的:虽然强迫症(OCD)常与神经性厌食症和神经性贪食症共发,但其与回避/限制性食物摄入障碍(ARFID)维度的关系尚不清楚。ARFID维度与强迫症之间的关联是否因性别而异也尚不清楚。我们按性别检查了ARFID维度与强迫症症状之间的关联,并考虑了抑郁和焦虑。方法:对ARFID基因与环境(ARFID- gen)研究中3120名15岁以上参与者的数据进行分析。ARFID维度(即感觉敏感性;食欲不振/对食物缺乏兴趣;以及对不良后果的恐惧)、强迫症症状、焦虑和抑郁采用有效的自我报告测量方法进行评估。我们使用一般线性模型评估ARFID维度与强迫症症状之间的关联,并对抑郁和焦虑进行调整。结果:ARFID维度与强迫症症状显著相关。在调整抑郁和焦虑后,这些关联减弱,但在ARFID的所有维度上仍然显著。ARFID维度与强迫症症状之间的关联因性别而异。结论:ARFID症状学与强迫症之间的关系值得在ARFID出现的发育谱系中进一步探索。在临床上,双向筛查可以提高诊断的清晰度,并为适当的干预提供信息。试验注册:ARFID-GEN已在clinicaltrials.gov注册(NCT05605067)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
European Eating Disorders Review
European Eating Disorders Review PSYCHOLOGY, CLINICAL-
CiteScore
8.90
自引率
7.50%
发文量
81
期刊介绍: European Eating Disorders Review publishes authoritative and accessible articles, from all over the world, which review or report original research that has implications for the treatment and care of people with eating disorders, and articles which report innovations and experience in the clinical management of eating disorders. The journal focuses on implications for best practice in diagnosis and treatment. The journal also provides a forum for discussion of the causes and prevention of eating disorders, and related health policy. The aims of the journal are to offer a channel of communication between researchers, practitioners, administrators and policymakers who need to report and understand developments in the field of eating disorders.
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