Glutameter- A pre-diagnostic biosensor to detect L-glutamine in cancer.

IF 4.4 4区生物学 Q1 BIOCHEMICAL RESEARCH METHODS

IEEE Transactions on NanoBioscience Pub Date : 2026-04-22 DOI:10.1109/TNB.2026.3686680

Gopikasri Manoharan, Ratan Kumar Chaudhary, M Muthu Meenakshi, V V R Sai, Swathi Sudhakar

引用次数: 0

Abstract

L-glutamine's role in cancer metabolism makes it a more versatile biomarker for cancer detection. A plasmonic fiberoptic absorption biosensor (P-FAB), an emerging technology that utilizes a compact U-shaped optical fiber with an enhanced evanescent field and plasmonic labels to give rise to an ultra-high analyte detection sensitivity, was employed to detect L-Glutamine (L-Gln) as a biomarker using a competitive immunoassay for early cancer detection.

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谷氨酰胺检测仪-一种用于检测癌症中l -谷氨酰胺的预诊断生物传感器。

l -谷氨酰胺在癌症代谢中的作用使其成为癌症检测的更通用的生物标志物。等离子体光纤吸收生物传感器（P-FAB）是一种新兴技术，它利用紧凑的u形光纤和增强的倏逝场和等离子体标签来产生超高的分析物检测灵敏度，采用竞争性免疫分析法检测l -谷氨酰胺（L-Gln）作为生物标志物，用于早期癌症检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

IEEE Transactions on NanoBioscience 工程技术-纳米科技

CiteScore

7.00

自引率

5.10%

发文量

197

审稿时长

>12 weeks

期刊介绍： The IEEE Transactions on NanoBioscience reports on original, innovative and interdisciplinary work on all aspects of molecular systems, cellular systems, and tissues (including molecular electronics). Topics covered in the journal focus on a broad spectrum of aspects, both on foundations and on applications. Specifically, methods and techniques, experimental aspects, design and implementation, instrumentation and laboratory equipment, clinical aspects, hardware and software data acquisition and analysis and computer based modelling are covered (based on traditional or high performance computing - parallel computers or computer networks).