Diagnostic utility of tubomanometry for patulous eustachian tube: A comparative study

IF 1.7 4区医学 Q2 OTORHINOLARYNGOLOGY

American Journal of Otolaryngology Pub Date : 2026-05-01 Epub Date: 2026-04-22 DOI:10.1016/j.amjoto.2026.104846

Xiaoling Shi , Ren Zhou , Yanbo Yin , Yunfeng Wang

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引用次数: 0

Abstract

Purpose

The current diagnosis of patulous Eustachian tube (PET) has limitations and cannot accurately assess its functional status. This study aims to validate tubomanometry (TMM) as an objective diagnostic tool for PET by analyzing pressure-specific R-values.

Methods

A retrospective cohort study was conducted involving 95 ears from 64 patients which were stratified into three groups: Definite PET (n = 26), Possible PET (n = 41), and Controls (n = 28). Diagnostic performance was evaluated by receiver operator characteristic (ROC) curve analysis to determine optimal R-value thresholds.

Results

The Definite PET group exhibited significantly lower R-values compared to the Possible PET and Control groups at all pressure levels (30 mbar: 0.27 ± 0.39 vs 0.40 ± 0.34 vs 0.99 ± 0.49, p < 0.001; 40 mbar: 0.39 ± 0.55 vs 0.54 ± 0.44 vs 0.75 ± 0.31, p = 0.001; 50 mbar: 0.32 ± 0.33 vs 0.41 ± 0.33 vs 0.70 ± 0.32, p < 0.001). The optimal diagnostic threshold was achieved at 30 mbar (R-value cutoff: 0.585; sensitivity: 75%, specificity: 77%, area under curve [AUC]: 0.802). Asymptomatic contralateral ears in unilateral PET cases exhibited R-values that were similar to healthy controls (p > 0.05).

Conclusion

TMM is a robust diagnostic tool for PET, with optimal clinical utility at 30 mbar. Pressure-specific R-value thresholds can differentiate the severity of PET and validate the status of asymptomatic ears in unilateral cases.

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咽鼓管扩张性诊断的比较研究。

目的：目前对扩张性咽鼓管（PET）的诊断存在局限性，不能准确评估其功能状态。本研究旨在通过分析压力特异性r值来验证TMM作为PET的客观诊断工具。方法：采用回顾性队列研究方法，将64例患者的95只耳朵分为三组：确定PET组（n = 26）、可能PET组（n = 41）和对照组（n = 28）。通过受试者操作特征（ROC）曲线分析评估诊断效果，以确定最佳r值阈值。结果：在所有压力水平（30mbar: 0.27±0.39 vs 0.40±0.34 vs 0.99±0.49,p 0.05）下，Definite PET组的r值明显低于Possible PET组和Control组。结论：TMM是PET的可靠诊断工具，在30mbar时具有最佳临床效用。压力特异性r值阈值可以区分PET的严重程度，并验证单侧病例中无症状耳的状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Otolaryngology 医学-耳鼻喉科学

CiteScore

4.40

自引率

4.00%

发文量

378

审稿时长

41 days

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