Plasma proteomic signatures of preclinical Alzheimer's disease in clinically unimpaired older adults.

IF 17.5 1区医学 Q1 NEUROSCIENCES

Molecular Neurodegeneration Pub Date : 2026-04-24 DOI:10.1186/s13024-026-00941-5

Alexandra N Trelle,Karly A Cody,Tran T Nguyen,Joseph R Winer,Skylar Weiss,Isha Sai,Tyler Ward,Gloria Cheng,Divya Channappa,Justin Mendiola,Amal Al-Rajhi,Keerthana Raghuraman,Sharon J Sha,Edward N Wilson,Tony Wyss-Coray,Holden T Maecker,Anthony D Wagner,Elizabeth C Mormino

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临床未受损老年人临床前阿尔茨海默病的血浆蛋白质组学特征

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Molecular Neurodegeneration 医学-神经科学

CiteScore

23.00

自引率

4.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Molecular Neurodegeneration, an open-access, peer-reviewed journal, comprehensively covers neurodegeneration research at the molecular and cellular levels. Neurodegenerative diseases, such as Alzheimer's, Parkinson's, Huntington's, and prion diseases, fall under its purview. These disorders, often linked to advanced aging and characterized by varying degrees of dementia, pose a significant public health concern with the growing aging population. Recent strides in understanding the molecular and cellular mechanisms of these neurodegenerative disorders offer valuable insights into their pathogenesis.