Occupational exposure assessment following a 99mTc radiopharmaceutical incident

IF 1.6 3区 化学 Q3 CHEMISTRY, ANALYTICAL
Akbar Abbasi, Serap Maden, Fatemeh Mirekhtiary
{"title":"Occupational exposure assessment following a 99mTc radiopharmaceutical incident","authors":"Akbar Abbasi,&nbsp;Serap Maden,&nbsp;Fatemeh Mirekhtiary","doi":"10.1007/s10967-026-10823-1","DOIUrl":null,"url":null,"abstract":"<div><p>Technetium-99 m (<sup>99m</sup>Tc) is a cornerstone isotope in nuclear medicine diagnostics, utilized globally for over four decades in clinics worldwide. However, accidental spills during handling pose risks of substantial occupational radiation exposure. This study modeled a simulated incident involving vial breakage and footwear contamination using the SkinDose simulator (v 1.3, developed by Renaissance Code Development -RCD). It evaluated both beta and gamma radiation pathways, calculating equivalent dose equivalents and probabilistic risks over exposure durations. Findings revealed that occupational skin dose limits are exceeded within 1–3 h, emphasizing the critical importance of immediate decontamination procedures. Moreover, the results underscore the often-overlooked contribution of gamma radiation in such scenarios. These insights challenge traditional dosimetry models, including VARSKIN, and strongly advocate for the adoption of advanced computational tools to refine and strengthen radioprotection frameworks in nuclear medicine practices.</p></div>","PeriodicalId":661,"journal":{"name":"Journal of Radioanalytical and Nuclear Chemistry","volume":"335 4","pages":"2875 - 2882"},"PeriodicalIF":1.6000,"publicationDate":"2026-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Radioanalytical and Nuclear Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10967-026-10823-1","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0

Abstract

Technetium-99 m (99mTc) is a cornerstone isotope in nuclear medicine diagnostics, utilized globally for over four decades in clinics worldwide. However, accidental spills during handling pose risks of substantial occupational radiation exposure. This study modeled a simulated incident involving vial breakage and footwear contamination using the SkinDose simulator (v 1.3, developed by Renaissance Code Development -RCD). It evaluated both beta and gamma radiation pathways, calculating equivalent dose equivalents and probabilistic risks over exposure durations. Findings revealed that occupational skin dose limits are exceeded within 1–3 h, emphasizing the critical importance of immediate decontamination procedures. Moreover, the results underscore the often-overlooked contribution of gamma radiation in such scenarios. These insights challenge traditional dosimetry models, including VARSKIN, and strongly advocate for the adoption of advanced computational tools to refine and strengthen radioprotection frameworks in nuclear medicine practices.

99mTc放射性药物事故后的职业暴露评估
锝- 99m (99mTc)是核医学诊断的基石同位素,在全球各地的诊所使用了40多年。然而,处理过程中的意外泄漏会造成大量职业辐射暴露的风险。本研究使用SkinDose模拟器(v1.3,由Renaissance Code Development -RCD开发)模拟了一个涉及瓶子破损和鞋类污染的模拟事件。它评估了β和γ辐射途径,计算了等效剂量当量和照射持续时间的概率风险。研究结果显示,职业性皮肤剂量限值在1-3小时内就会超过,这强调了立即进行去污处理的重要性。此外,研究结果强调了伽马辐射在这种情况下经常被忽视的作用。这些见解挑战了包括VARSKIN在内的传统剂量学模型,并强烈主张采用先进的计算工具来完善和加强核医学实践中的辐射防护框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
2.80
自引率
18.80%
发文量
504
审稿时长
2.2 months
期刊介绍: An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书