C Schöffer, C-C Del'Agnese, E-L Marder, L-M Oliveira, R-P Antoniazzi
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引用次数: 0
Abstract
Background: Chronic kidney disease (CKD) is associated with a higher occurrence of periodontitis, which may be linked to negative psychosocial and physical impacts on the lives of patients affected by both conditions. Therefore, the aim of this systematic review was to evaluate whether periodontal conditions influence OHRQoL in patients with CKD.
Materials and methods: Electronic searches were performed in five databases up to May 2025. Observational studies conducted in individuals with CKD that investigated the relationship between periodontal conditions through clinical examinations and OHRQoL, were included. Meta-analyses were performed to estimate the mean difference (MD) in OHRQoL, as well as the correlation.
Results: Out of the 2036 potentially eligible reports, 7 studies of patients with end-stage renal disease (ESRD) were included. Pooled estimates demonstrated that OHIP-14 scores are higher in individuals with ESRD compared to healthy controls. Impaired OHRQoL can be attributed to the higher prevalence of periodontitis in renal patients. Considering a score-response gradient, those with stage III/IV periodontitis had higher OHIP-14 scores compared to patients without periodontitis or with stage I/II periodontitis (MD:1.88; 95%CI: 0.67-3.09; p=0.002). Pooled estimates demonstrated a weak but significant positive correlation between periodontal probing depth (r=0.145; p=0.028) and plaque index (r=0.385; p<0.001) with OHIP-14 scores.
Conclusions: Severe periodontitis, along with higher probing depth and plaque scores, negatively influences the OHRQoL of patients with ESRD. However, these relationships show a small magnitude.
期刊介绍：
1. Oral Medicine and Pathology:
Clinicopathological as well as medical or surgical management aspects of
diseases affecting oral mucosa, salivary glands, maxillary bones, as well as
orofacial neurological disorders, and systemic conditions with an impact on
the oral cavity.
2. Oral Surgery:
Surgical management aspects of diseases affecting oral mucosa, salivary glands,
maxillary bones, teeth, implants, oral surgical procedures. Surgical management
of diseases affecting head and neck areas.
3. Medically compromised patients in Dentistry:
Articles discussing medical problems in Odontology will also be included, with
a special focus on the clinico-odontological management of medically compromised patients, and considerations regarding high-risk or disabled patients.
4. Implantology
5. Periodontology
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