Outside Back Cover: Reaction-Based Ratiometric Sensors for Simultaneous Multi-Bio-Analyte Imaging in Living Cells Using Spontaneous Raman Scattering (Angew. Chem. 15/2026)
{"title":"Outside Back Cover: Reaction-Based Ratiometric Sensors for Simultaneous Multi-Bio-Analyte Imaging in Living Cells Using Spontaneous Raman Scattering (Angew. Chem. 15/2026)","authors":"Sujit K Das, Heqi Xi, Itsuki Yamamoto, Katsumasa Fujita, Ankona Datta","doi":"10.1002/ange.2026-m2702055900","DOIUrl":null,"url":null,"abstract":"<p>Employing the ‘push-pull’ effect by incorporating donor-acceptor moieties across alkynes achieves highly sensitive Raman sensors. Activity-based alkyne-tag Raman sensors, ABATaRs, enable Raman imaging of bio-analytes at low sensor concentrations and the first multiplexed ‘logic-gate’ imaging of metal ions and reactive oxygen species, on a spontaneous Raman microscopy platform in live cells. More in the Research Article (e22980), Ankona Datta and co-workers.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7803,"journal":{"name":"Angewandte Chemie","volume":"138 15","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ange.2026-m2702055900","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Angewandte Chemie","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ange.2026-m2702055900","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/3/9 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Employing the ‘push-pull’ effect by incorporating donor-acceptor moieties across alkynes achieves highly sensitive Raman sensors. Activity-based alkyne-tag Raman sensors, ABATaRs, enable Raman imaging of bio-analytes at low sensor concentrations and the first multiplexed ‘logic-gate’ imaging of metal ions and reactive oxygen species, on a spontaneous Raman microscopy platform in live cells. More in the Research Article (e22980), Ankona Datta and co-workers.