Screening, monitoring and treatment of interstitial lung disease in systemic sclerosis.

IF 4.8 2区医学 Q1 RHEUMATOLOGY

Best Practice & Research in Clinical Rheumatology Pub Date : 2026-04-15 DOI:10.1016/j.berh.2026.102131

Sindhu R Johnson, Elana J Bernstein

引用次数: 0

Abstract

Interstitial lung disease (ILD) is a major source of morbidity and the leading cause of mortality in people with systemic sclerosis (SSc). There have been advancements in the treatment of ILD. In this article, we review the American College of Rheumatology (ACR) and the American College of Chest Physicians (CHEST) guidelines for the screening, monitoring and treatment of SSc-ILD. We highlight additional pharmacologic and non-pharmacologic interventions that should be considered in those with SSc-ILD. Finally, we summarize the ACR guidelines for vaccinations in those with SSc-ILD, and recommendations for holding immunosuppressive therapies to maximize immunogenicity of the vaccines.

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系统性硬化症间质性肺疾病的筛查、监测和治疗。

间质性肺疾病（ILD）是系统性硬化症（SSc）患者发病和死亡的主要原因。ILD的治疗已经取得了进展。在本文中，我们回顾了美国风湿病学会（ACR）和美国胸科医师学会（Chest）筛查、监测和治疗SSc-ILD的指南。我们强调了SSc-ILD患者应考虑的其他药物和非药物干预措施。最后，我们总结了针对SSc-ILD患者的ACR疫苗接种指南，并建议进行免疫抑制治疗以最大限度地提高疫苗的免疫原性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Best Practice & Research in Clinical Rheumatology 医学-风湿病学

CiteScore

9.40

自引率

0.00%

发文量

审稿时长

27 days

期刊介绍： Evidence-based updates of best clinical practice across the spectrum of musculoskeletal conditions. Best Practice & Research: Clinical Rheumatology keeps the clinician or trainee informed of the latest developments and current recommended practice in the rapidly advancing fields of musculoskeletal conditions and science. The series provides a continuous update of current clinical practice. It is a topical serial publication that covers the spectrum of musculoskeletal conditions in a 4-year cycle. Each topic-based issue contains around 200 pages of practical, evidence-based review articles, which integrate the results from the latest original research with current clinical practice and thinking to provide a continuous update. Each issue follows a problem-orientated approach that focuses on the key questions to be addressed, clearly defining what is known and not known. The review articles seek to address the clinical issues of diagnosis, treatment and patient management. Management is described in practical terms so that it can be applied to the individual patient. The serial is aimed at the physician in both practice and training.