Mental Health and quality of Life in Inflammatory Bowel disease: Cross-sectional Study on its Impact.

IF 1.9 4区医学 Q3 GASTROENTEROLOGY & HEPATOLOGY

Gastroenterologia y hepatologia Pub Date : 2026-04-15 DOI:10.1016/j.gastrohep.2026.502763

Vanesa Gallardo Arriero, Marta Calvo Moya, Rocío de Lucas Téllez de Meneses, Irene González Partida, Belén Botella Mateu, Virginia Matallana Royo, Pablo Bella Castillo, Macarena González Rodríguez, Maribel Vera Mendoza

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引用次数: 0

Abstract

Objective: Inflammatory Bowel Disease (IBD) negatively impacts patients' quality of life. This study aims to evaluate the psychological impact and quality of life in patients with IBD.

Patients and methods: A cross-sectional study was conducted involving IBD patients treated at HUPHM. Validated questionnaires were used to assess patients' mental health. Clinical activity was evaluated using the Harvey-Bradshaw Index and the Partial Mayo Score. Clinical data were also collected.

Results: A total of 272 patients were included. Seventy-eight percent experienced some degree of psychological impairment, and 68% reported a negative impact on their quality of life. Anxiety showed a median score of 11 (IQR: 10-13) and stress a median of 24 (IQR: 16-31), representing the most frequent psychological disturbances. Quality of life and fatigue results reflected significant impairment, with fatigue being more prevalent in women (52%, p=0.027) and associated with higher stress levels (p=0.0013) and poorer quality of life (p=0.014). Patients with Crohn's disease exhibited worse quality of life compared to those with ulcerative colitis (median score: 46 [IQR: 34-55] vs. 49 [IQR: 41-55], p=0.04). In the occupational domain, patients with work disability showed greater psychological impairment and poorer quality of life (p=0.001). Finally, patients without prior surgery demonstrated better quality of life (p=0.032).

Conclusions: The high prevalence of psychological comorbidities in IBD highlights the need for approaches that incorporate psychological assessment and intervention.

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炎症性肠病患者的心理健康和生活质量：其影响的横断面研究

目的：炎症性肠病（IBD）对患者生活质量的负面影响。本研究旨在评估IBD患者的心理影响和生活质量。患者和方法：对在HUPHM治疗的IBD患者进行了一项横断面研究。使用有效的问卷来评估患者的心理健康状况。临床活动评估采用哈维-布拉德肖指数和部分梅奥评分。同时收集临床资料。结果：共纳入272例患者。78%的人经历了某种程度的心理障碍，68%的人报告说他们的生活质量受到了负面影响。焦虑的中位数得分为11 (IQR: 10-13)，压力的中位数得分为24 (IQR: 16-31)，代表了最常见的心理障碍。生活质量和疲劳结果反映了显著的损害，疲劳在女性中更为普遍（52%,p=0.027），并与较高的压力水平（p=0.0013）和较差的生活质量（p=0.014）相关。与溃疡性结肠炎患者相比，克罗恩病患者表现出更差的生活质量（中位评分：46 [IQR: 34-55]对49 [IQR: 41-55]， p=0.04）。在职业领域，工作残疾患者表现出更大的心理障碍和更差的生活质量（p=0.001）。最后，未手术的患者表现出更好的生活质量（p=0.032）。结论：IBD中心理合并症的高发突出了将心理评估和干预相结合的方法的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Gastroenterologia y hepatologia GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

1.50

自引率

10.50%

发文量

147

审稿时长

48 days

期刊介绍： Gastroenterology and Hepatology is the first journal to cover the latest advances in pathology of the gastrointestinal tract, liver, pancreas, and bile ducts, making it an indispensable tool for gastroenterologists, hepatologists, internists and general practitioners.