Outcomes of micropulse cyclophotocoagulation for refractory glaucoma in children.

IF 2.7 3区医学 Q2 OPHTHALMOLOGY

Japanese Journal of Ophthalmology Pub Date : 2026-07-01 Epub Date: 2026-04-16 DOI:10.1007/s10384-026-01354-z

Tomoyo Yoshida, Tadashi Yokoi, Hazuki Anzai, Ayaka Nishida, Sachiko Nishina

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引用次数: 0

Abstract

Purpose: To evaluate the outcomes of micropulse transscleral cyclophotocoagulation (MP-CPC) for refractory glaucoma in children.

Study design: Retrospective study.

Methods: We evaluated the data from children with refractory glaucoma who underwent MP-CPC from July 2022 to December 2024 at the National Center for Child Health and Development and who were followed up for at least 3 months. The retrospective analysis included age; glaucoma type; history of glaucoma surgery; intraocular pressure (IOP) at baseline and at 1, 3, and 6 months postoperatively; medication score administered before and after surgery; visual acuity; and complications.

Results: Twenty-nine eyes of 24 patients (average age, 101.3 ± 68.1 months) were included in this study. The most common types of glaucoma were glaucoma associated with nonacquired ocular anomalies and glaucoma after cataract surgery, accounting for 11 eyes (37.9%). The average number of glaucoma surgeries performed before treatment was 1.9 ± 1.6. The average follow-up period was 16.1 ± 7.9 months. Using a mixed-effects model, the mean IOP decreased by -9.8 mm Hg at 1 month (P <.01), -7.5 mm Hg at 3 months (P <.01), and -7.4 mm Hg at 6 months (P <.01). The median medication score (interquartile range) decreased from 5 (4-6) preoperatively to 4 (3-5) at 1, 3, and 6 months postoperatively. After undergoing the first MP-CPC, 19 eyes (65.5%) required reoperation for glaucoma. Eleven eyes (37.9%) required reoperation within 6 months postoperatively, and 17 eyes (58.6%) required reoperation within 1 year.

Conclusion: MP-CPC effectively reduces IOP in children with refractory glaucoma without causing visual impairment or serious complications.

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微脉冲光凝治疗儿童难治性青光眼的疗效。

目的：评价微脉冲经巩膜光凝治疗儿童难治性青光眼的疗效。研究设计：回顾性研究。方法：我们评估了2022年7月至2024年12月在国家儿童健康与发展中心接受MP-CPC治疗的顽固性青光眼儿童的数据，并对这些儿童进行了至少3个月的随访。回顾性分析包括年龄；青光眼的类型;青光眼手术史；基线及术后1、3、6个月的眼内压（IOP）；术前、术后用药评分；视力;和并发症。结果：纳入24例患者29只眼，平均年龄101.3±68.1个月。青光眼最常见的类型是伴有非获得性眼异常的青光眼和白内障术后青光眼，占11只眼（37.9%）。治疗前平均青光眼手术次数为1.9±1.6次。平均随访16.1±7.9个月。采用混合效应模型，1个月后平均IOP下降-9.8 mm Hg (P)。结论：MP-CPC可有效降低顽固性青光眼患儿的IOP，且无视力损害或严重并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Japanese Journal of Ophthalmology 医学-眼科学

CiteScore

4.80

自引率

8.30%

发文量

审稿时长

6-12 weeks

期刊介绍： The Japanese Journal of Ophthalmology (JJO) was inaugurated in 1957 as a quarterly journal published in English by the Ophthalmology Department of the University of Tokyo, with the aim of disseminating the achievements of Japanese ophthalmologists worldwide. JJO remains the only Japanese ophthalmology journal published in English. In 1997, the Japanese Ophthalmological Society assumed the responsibility for publishing the Japanese Journal of Ophthalmology as its official English-language publication. Currently the journal is published bimonthly and accepts papers from authors worldwide. JJO has become an international interdisciplinary forum for the publication of basic science and clinical research papers.