Effects of HIV and azidothymidine on Alzheimer's-like pathology and amyloid beta transporters in hu-PBL-NSG mice, brain endothelial amyloid beta uptake and endothelial barrier integrity.

IF 6.2 1区医学 Q1 NEUROSCIENCES

Fluids and Barriers of the CNS Pub Date : 2026-04-16 DOI:10.1186/s12987-026-00807-4

Biju Bhargavan, Narendran Annadurai, Georgette D Kanmogne

引用次数: 0

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HIV和azidothymidine对hu-PBL-NSG小鼠阿尔茨海默病样病理和β -淀粉样蛋白转运蛋白、脑内皮β -淀粉样蛋白摄取和内皮屏障完整性的影响

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fluids and Barriers of the CNS Neuroscience-Developmental Neuroscience

CiteScore

10.70

自引率

8.20%

发文量

审稿时长

14 weeks

期刊介绍： "Fluids and Barriers of the CNS" is a scholarly open access journal that specializes in the intricate world of the central nervous system's fluids and barriers, which are pivotal for the health and well-being of the human body. This journal is a peer-reviewed platform that welcomes research manuscripts exploring the full spectrum of CNS fluids and barriers, with a particular focus on their roles in both health and disease. At the heart of this journal's interest is the cerebrospinal fluid (CSF), a vital fluid that circulates within the brain and spinal cord, playing a multifaceted role in the normal functioning of the brain and in various neurological conditions. The journal delves into the composition, circulation, and absorption of CSF, as well as its relationship with the parenchymal interstitial fluid and the neurovascular unit at the blood-brain barrier (BBB).