{"title":"Hyperglycemia with Ketoacidosis following Acute Necrotizing Pancreatitis: A Case Suggestive of Pancreatogenic Diabetes.","authors":"Ponvijaya Yadav, Avuthu Hemanjali, Divam Prakash Singh, Adheesh Phalke","doi":"10.4103/aam.aam_735_25","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>A 44-year-old female, known case of hypertension and hypothyroidism, presented with severe epigastric pain and vomiting. Laboratory evaluation showed significant hyperglycemia (440 mg/dL), ketonuria, and metabolic acidosis (pH - 7.3, HCO - 10.6 mEq/L), consistent with Diabetic Ketoacidosis. Amylase and lipase levels were elevated. Imaging showed acute necrotising pancreatitis with 70%-80% necrosis (modified Computed tomography severity score inde × 8/10). The patient was shifted to the intensive care unit, where blood sugar levels and hypertension were strictly controlled. The patient was vitally stable and had shown significant clinical improvement. She was discharged on injectable insulin, oral antihypertensive and hypothyroid medication and is on regular follow-up.</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aam.aam_735_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: A 44-year-old female, known case of hypertension and hypothyroidism, presented with severe epigastric pain and vomiting. Laboratory evaluation showed significant hyperglycemia (440 mg/dL), ketonuria, and metabolic acidosis (pH - 7.3, HCO - 10.6 mEq/L), consistent with Diabetic Ketoacidosis. Amylase and lipase levels were elevated. Imaging showed acute necrotising pancreatitis with 70%-80% necrosis (modified Computed tomography severity score inde × 8/10). The patient was shifted to the intensive care unit, where blood sugar levels and hypertension were strictly controlled. The patient was vitally stable and had shown significant clinical improvement. She was discharged on injectable insulin, oral antihypertensive and hypothyroid medication and is on regular follow-up.
期刊介绍：
The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.
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