Personality and Psychotic-Like Features in Post-Traumatic Stress Disorder With Severe Depression: An Minnesota Multiphasic Personality Inventory-2 Schizophrenia Scale Analysis.

IF 1.8 4区医学 Q3 PSYCHIATRY

Psychiatry Investigation Pub Date : 2026-04-01 Epub Date: 2026-04-06 DOI:10.30773/pi.2025.0403

Young Kyung Moon, Kayoung Song, Sora Lee, Hayun Choi

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引用次数: 0

Abstract

Objective: We aimed to identify factors influencing the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) Schizophrenia scale (T_Sc) among patients with post-traumatic stress disorder (PTSD) who underwent both Clinician Administered PTSD Scales (CAPS) and MMPI-2.

Methods: We retrospectively reviewed 119 patients who underwent CAPS and MMPI-2 from May 2013 to November 2022 at Veteran Health Service Medical Center, Seoul, Korea. Based on the Korean-Beck Depression Inventory-II (K-BDI-II), the PTSD patients (n=64) were classified into severe depression group (K-BDI-II ≥29; n=43) and less-severe depression group (K-BDI-II <29; n=21). Correlations among K-BDI-II, CAPS, and MMPI-2 scales were examined, and multiple linear regression analyses were performed to identify predictors of T_Sc after adjusting for potential confounders (e.g., age, sex, CAPS scores, MMPI-2 scales).

Results: The severe depression group had significantly higher T_Sc scores (p<0.001). T_Sc was strongly correlated with K-BDI-II scores (r=0.70, p<0.001). In regression analysis, PTSD patients with severe depression (K-BDI-II ≥29) showed higher T_Sc than those without severe depression after adjustment for age, sex, and CAPS; however, this association was attenuated after further adjustment for additional covariates. Multiple linear regression analyses revealed that MMPI-2 restructured clinical (RC) scales, -particularly Demoralization was associated with T_Sc score.

Conclusion: PTSD patients frequently exhibit elevated T_Sc scores, particularly when severe depression coexists. However, the independent contribution of depression diminishes when underlying personality and psychopathological traits including demoralization are considered. These findings highlight the necessity of individualized MMPI-2 interpretation and tailored clinical strategies for this subgroup.

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创伤后应激障碍伴严重抑郁症患者的人格和精神样特征：明尼苏达多相人格量表-2精神分裂症量表分析。

目的：本研究旨在确定影响创伤后应激障碍（PTSD）患者明尼苏达多相人格量表-2 （MMPI-2）精神分裂症量表（T_Sc）的因素，这些患者同时接受了临床医生管理的PTSD量表（CAPS）和MMPI-2。方法：我们回顾性分析了2013年5月至2022年11月在韩国首尔退伍军人卫生服务医疗中心接受CAPS和MMPI-2治疗的119例患者。根据Korean-Beck抑郁量表- ii (K-BDI-II)，将64例PTSD患者分为重度抑郁组（K-BDI-II≥29;n=43）和轻度抑郁组（K-BDI-II）。结果：重度抑郁组T_Sc得分显著高于轻度抑郁组(p)。结论：PTSD患者常出现T_Sc得分升高，尤其是重度抑郁患者。然而，当考虑到潜在的人格和精神病理特征（包括士气低落）时，抑郁的独立贡献就会减少。这些发现强调了个体化MMPI-2解释和为该亚组量身定制临床策略的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Psychiatry Investigation PSYCHIATRY-

CiteScore

4.10

自引率

3.70%

发文量

105

审稿时长

6-12 weeks

期刊介绍： The Psychiatry Investigation is published on the 25th day of every month in English by the Korean Neuropsychiatric Association (KNPA). The Journal covers the whole range of psychiatry and neuroscience. Both basic and clinical contributions are encouraged from all disciplines and research areas relevant to the pathophysiology and management of neuropsychiatric disorders and symptoms, as well as researches related to cross cultural psychiatry and ethnic issues in psychiatry. The Journal publishes editorials, review articles, original articles, brief reports, viewpoints and correspondences. All research articles are peer reviewed. Contributions are accepted for publication on the condition that their substance has not been published or submitted for publication elsewhere. Authors submitting papers to the Journal (serially or otherwise) with a common theme or using data derived from the same sample (or a subset thereof) must send details of all relevant previous publications and simultaneous submissions. The Journal is not responsible for statements made by contributors. Material in the Journal does not necessarily reflect the views of the Editor or of the KNPA. Manuscripts accepted for publication are copy-edited to improve readability and to ensure conformity with house style.