Flexible Personalized Occlusion Therapy: A New Approach to Enhance Compliance and Efficacy in Amblyopia Treatment in Morocco.

IF 0.9 Q3 OPHTHALMOLOGY

Journal of Current Ophthalmology Pub Date : 2026-03-18 eCollection Date: 2025-07-01 DOI:10.4103/joco.joco_90_25

Mustapha Jaouhari, Chaimae El Harrak, Farida Bentayeb, Youssef El Merabet

{"title":"Flexible Personalized Occlusion Therapy: A New Approach to Enhance Compliance and Efficacy in Amblyopia Treatment in Morocco.","authors":"Mustapha Jaouhari, Chaimae El Harrak, Farida Bentayeb, Youssef El Merabet","doi":"10.4103/joco.joco_90_25","DOIUrl":null,"url":null,"abstract":"Purpose: To evaluate the effectiveness of flexible personalized occlusion therapy compared to standard personalized and fixed occlusion strategies in improving visual acuity in children with amblyopia. It also seeks to analyze the impact of treatment flexibility on patient adherence and total effective dose (TED).Methods: A total of 90 children with amblyopia participated in this prospective study. Participants were divided into three groups: Flexible personalized occlusion, standard personalized occlusion, and standard fixed occlusion. Visual acuity was assessed at baseline and monitored monthly for 12 weeks. Treatment adherence was measured using TED. Statistical analyses included one-way analysis of variance (ANOVA) and repeated-measures ANOVA to compare visual acuity improvements among groups.Results: Baseline visual acuity was comparable across groups (P > 0.05). By the final assessment, the Flexible Personalized Occlusion and Standard Personalized Occlusion groups achieved similar visual acuity improvements (0.2 ± 0.05 logMAR and 0.2 ± 0.04 logMAR, respectively), whereas the Standard Fixed Occlusion group had a slightly smaller improvement, reaching 0.25 ± 0.09 logMAR. The flexible group exhibited the lowest TED (295.4 ± 56 h), suggesting higher efficiency in treatment delivery.Conclusions: Flexible personalized occlusion therapy demonstrated comparable efficacy to standard occlusion strategies while offering greater flexibility and potentially enhancing patient engagement. These findings support the adoption of personalized and adaptable occlusion regimens in amblyopia management.","PeriodicalId":15423,"journal":{"name":"Journal of Current Ophthalmology","volume":"37 3","pages":"352-358"},"PeriodicalIF":0.9000,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13075914/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Current Ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/joco.joco_90_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To evaluate the effectiveness of flexible personalized occlusion therapy compared to standard personalized and fixed occlusion strategies in improving visual acuity in children with amblyopia. It also seeks to analyze the impact of treatment flexibility on patient adherence and total effective dose (TED).

Methods: A total of 90 children with amblyopia participated in this prospective study. Participants were divided into three groups: Flexible personalized occlusion, standard personalized occlusion, and standard fixed occlusion. Visual acuity was assessed at baseline and monitored monthly for 12 weeks. Treatment adherence was measured using TED. Statistical analyses included one-way analysis of variance (ANOVA) and repeated-measures ANOVA to compare visual acuity improvements among groups.

Results: Baseline visual acuity was comparable across groups (P > 0.05). By the final assessment, the Flexible Personalized Occlusion and Standard Personalized Occlusion groups achieved similar visual acuity improvements (0.2 ± 0.05 logMAR and 0.2 ± 0.04 logMAR, respectively), whereas the Standard Fixed Occlusion group had a slightly smaller improvement, reaching 0.25 ± 0.09 logMAR. The flexible group exhibited the lowest TED (295.4 ± 56 h), suggesting higher efficiency in treatment delivery.

Conclusions: Flexible personalized occlusion therapy demonstrated comparable efficacy to standard occlusion strategies while offering greater flexibility and potentially enhancing patient engagement. These findings support the adoption of personalized and adaptable occlusion regimens in amblyopia management.

查看原文本刊更多论文

灵活的个性化闭塞治疗：提高摩洛哥弱视治疗依从性和疗效的新途径。

目的：评价灵活个体化遮蔽治疗与标准个体化和固定遮蔽治疗在改善弱视儿童视力方面的效果。它还试图分析治疗灵活性对患者依从性和总有效剂量（TED）的影响。方法：对90例弱视儿童进行前瞻性研究。参与者分为三组：灵活的个性化咬合、标准的个性化咬合和标准的固定咬合。在基线时评估视力并每月监测12周。使用TED测量治疗依从性。统计分析包括单因素方差分析（ANOVA）和重复测量方差分析（repeated-measures ANOVA）来比较各组之间的视力改善情况。结果：两组间基线视力具有可比性（P < 0.05）。通过最终评估，灵活个性化闭塞组和标准个性化闭塞组的视力改善程度相似（分别为0.2±0.05 logMAR和0.2±0.04 logMAR），而标准固定闭塞组的改善程度略小，为0.25±0.09 logMAR。柔韧组的TED最低（295.4±56 h），提示治疗递送效率更高。结论：灵活的个性化咬合治疗显示出与标准咬合策略相当的疗效，同时提供更大的灵活性并潜在地提高患者的参与度。这些发现支持在弱视治疗中采用个性化和适应性强的闭塞治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Current Ophthalmology OPHTHALMOLOGY-

CiteScore

2.50

自引率

6.70%

发文量

审稿时长

8 weeks

期刊介绍： Peer Review under the responsibility of Iranian Society of Ophthalmology Journal of Current Ophthalmology, the official publication of the Iranian Society of Ophthalmology, is a peer-reviewed, open-access, scientific journal that welcomes high quality original articles related to vision science and all fields of ophthalmology. Journal of Current Ophthalmology is the continuum of Iranian Journal of Ophthalmology published since 1969.