Spherical Skin Model: Stratified Co-Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening (Adv. Healthcare Mater. 13/2026)

IF 9.6 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2026-04-08 DOI:10.1002/adhm.70869

Elisa Lenzi, Nadia Vertti-Quintero, Julien Husson, Anne-Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud

引用次数: 0

Abstract

Skin Model

This cover art illustrates a proposed Spherical Skin Model (SSM), featuring a core-shell structure that mimics the human dermis-epidermis organization. The SSMs are used to screen active ingredients with potential antioxidant benefits for the cells within the model. Their high reproducibility and ease of handling enable efficient high-throughput screening. More details can be found in the Research Article by Nadia Vertti-Quintero, Charles N. Baroud, and co-workers (DOI: 10.1002/adhm.202503250).

Abstract Image

查看原文本刊更多论文

球形皮肤模型：成纤维细胞和角质形成细胞在球形珠上分层共培养的化合物筛选（Adv. Healthcare Mater. 13/2026）

这个封面艺术说明了一个提议的球形皮肤模型（SSM），具有模仿人类真皮-表皮组织的核-壳结构。ssm用于筛选具有潜在抗氧化作用的活性成分，用于模型内的细胞。它们的高再现性和易于处理使高效的高通量筛选成为可能。更多细节可以在Nadia Vertti-Quintero， Charles N. Baroud及其同事的研究文章中找到（DOI: 10.1002/ admm .202503250）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.