T. A. Akopova, T. N. Popyrina, A. Ya. Alkhair, P. L. Ivanov, O. V. Beznaeva, I. A. Kirsh
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引用次数: 0
Abstract
In this paper, we describe mechanochemical approach as an environmentally friendly method to obtain a number of products based on chitosan. Their antibacterial activity against Bacillus subtilis and Escherichia coli was assessed. It was shown for the first time that both the original chitosan obtained by the mechanochemical method and its derivatives and copolymers with biocompatible synthetic and natural polymers have moderate activity against Gram-positive bacteria and weak activity against Gram-negative bacteria. The proposed approach is promising for the creation of biologically active solid compositions capable of being processed into final products due to ultradispersion and gelation in water with the possibility of use in the form of hydrogels, sprays, sponge and film materials.
期刊介绍：
Applied Biochemistry and Microbiology is an international peer reviewed journal that publishes original articles on biochemistry and microbiology that have or may have practical applications. The studies include: enzymes and mechanisms of enzymatic reactions, biosynthesis of low and high molecular physiologically active compounds; the studies of their structure and properties; biogenesis and pathways of their regulation; metabolism of producers of biologically active compounds, biocatalysis in organic synthesis, applied genetics of microorganisms, applied enzymology; protein and metabolic engineering, biochemical bases of phytoimmunity, applied aspects of biochemical and immunochemical analysis; biodegradation of xenobiotics; biosensors; biomedical research (without clinical studies). Along with experimental works, the journal publishes descriptions of novel research techniques and reviews on selected topics.
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