Synthesis of Chitosan-Stabilized Silver Nanoparticles under In Situ and Ex-Situ Conditions and Their Biological Applications

IF 1.1 4区生物学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Applied Biochemistry and Microbiology Pub Date : 2026-03-02 DOI:10.1134/S0003683825602665

M. R. Kodirkhonov, N. R. Vokhidova, S. Sh. Rashidova, J. M. Kadirkhanov, N. J. Abdullayev

引用次数: 0

Abstract

Silver nanoparticles were obtained in the presence of 2-propanol under both in situ and ex situ conditions. It was established that the hydrodynamic radius and polydispersity of the particles increase with rising pH (6.0–11.0) due to the accelerated reduction of Ag⁺ ions. Variation of the chitosan molecular-weight parameters and the chitosan/Ag⁺ molar ratio (5–30) enabled controlled formation of stabilized nanoparticles ranging from 20 to 140 nm. The chitosan–silver nanoparticle dispersions in 0.2–0.5% aqueous acetic solutions demonstrated pronounced fungicidal activity against Fusarium solani 169, Fusarium oxysporum 280, and Verticillium dahliae 57, producing sterile zones of 31–34 mm.

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壳聚糖稳定纳米银的原位和非原位合成及其生物学应用

在原位和非原位条件下，在2-丙醇存在下获得了银纳米颗粒。结果表明，随着pH（6.0 ~ 11.0）的升高，颗粒的水动力半径和多分散性增加，这是由于Ag+离子的加速还原。改变壳聚糖的分子量参数和壳聚糖/Ag+的摩尔比（5-30），可以在20 ~ 140 nm范围内形成稳定的纳米颗粒。壳聚糖-银纳米颗粒分散体在0.2-0.5%的醋酸水溶液中对番茄枯萎菌169、尖孢镰刀菌280和大水花黄萎病菌57表现出明显的杀真菌活性，产生31-34 mm的无菌区。

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来源期刊

Applied Biochemistry and Microbiology 生物-生物工程与应用微生物

CiteScore

1.70

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Applied Biochemistry and Microbiology is an international peer reviewed journal that publishes original articles on biochemistry and microbiology that have or may have practical applications. The studies include: enzymes and mechanisms of enzymatic reactions, biosynthesis of low and high molecular physiologically active compounds; the studies of their structure and properties; biogenesis and pathways of their regulation; metabolism of producers of biologically active compounds, biocatalysis in organic synthesis, applied genetics of microorganisms, applied enzymology; protein and metabolic engineering, biochemical bases of phytoimmunity, applied aspects of biochemical and immunochemical analysis; biodegradation of xenobiotics; biosensors; biomedical research (without clinical studies). Along with experimental works, the journal publishes descriptions of novel research techniques and reviews on selected topics.