Chitosan and Its Derivatives: Applied Aspects

IF 1.1 4区生物学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Applied Biochemistry and Microbiology Pub Date : 2026-04-16 DOI:10.1134/S0003683825604718

T. A. Zhilkina, A. M. Kamionskaya, V. P. Varlamov, I. V. Yakovleva

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引用次数: 0

Abstract

This review presents a summary of the diverse range of chitosan applications that have been developed recently: from biomedicine, agrobiotechnology, biostimulation, and bioprotection to climate change adaptation, among others. The focus is on the functionalization and controlled optimization of key biopolymer parameters: degree of polymerization, degree of acetylation, distribution of acetylated blocks within the biopolymer chain, density, and cross-linking reagents. The development of chitosan-based systems for encapsulating drugs and vaccines described in this review improves precision drug delivery. The biologization of agriculture is reflected in this review through studies devoted to the use of chitosan as a protective agent against abiotic stresses, such as drought, high and low temperatures, and soil salinization. By focusing on new strategies for the combined use of chitosan and plant-associated soil bacteria, the use of chitosan nanoparticles demonstrates the expanding scope of biopolymer applications in the agricultural sector. The presented discussion of the mechanism of chitosan action on the immune system of plants provides a deeper understanding of how to achieve the targeted effects of bioprotection and biostimulation.

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壳聚糖及其衍生物：应用方面

本文综述了近年来壳聚糖在生物医学、农业生物技术、生物刺激、生物保护和适应气候变化等方面的广泛应用。重点是关键生物聚合物参数的功能化和可控优化：聚合度，乙酰化程度，生物聚合物链中乙酰化块的分布，密度和交联试剂。基于壳聚糖的药物和疫苗包封系统的发展提高了药物的精准输送。本文通过壳聚糖作为抗干旱、高温、低温、土壤盐碱化等非生物胁迫的保护剂的研究，反映了农业的生物化。通过关注壳聚糖与植物相关土壤细菌联合使用的新策略，壳聚糖纳米颗粒的使用表明生物聚合物在农业领域的应用范围正在扩大。通过对壳聚糖作用于植物免疫系统的机理的探讨，对如何实现生物保护和生物刺激的靶向作用有了更深入的了解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Applied Biochemistry and Microbiology 生物-生物工程与应用微生物

CiteScore

1.70

自引率

12.50%

发文量

审稿时长

6-12 weeks

期刊介绍： Applied Biochemistry and Microbiology is an international peer reviewed journal that publishes original articles on biochemistry and microbiology that have or may have practical applications. The studies include: enzymes and mechanisms of enzymatic reactions, biosynthesis of low and high molecular physiologically active compounds; the studies of their structure and properties; biogenesis and pathways of their regulation; metabolism of producers of biologically active compounds, biocatalysis in organic synthesis, applied genetics of microorganisms, applied enzymology; protein and metabolic engineering, biochemical bases of phytoimmunity, applied aspects of biochemical and immunochemical analysis; biodegradation of xenobiotics; biosensors; biomedical research (without clinical studies). Along with experimental works, the journal publishes descriptions of novel research techniques and reviews on selected topics.