Baseline Prolonged QRS Duration May Predict In-Hospital Outcomes of Patients With Acute Myocarditis: Multicenter Observational Study.

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Circulation reports Pub Date : 2026-02-19 eCollection Date: 2026-04-10 DOI:10.1253/circrep.CR-25-0306

Ayano Yoshida, Takuma Takada, Eiji Shibahashi, Takuro Abe, Kensuke Shimazaki, Takanori Kawamoto, Motoko Kametani, Natsuko Satomi, Kazuho Kamishima, Takashi Saito, Erina Tomari, Atsushi Honda, Atsushi Takagi, Kyomi Ashihara, Junichi Yamaguchi, Kentaro Jujo

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Abstract

Background: The prognosis of acute myocarditis (AM) is difficult to predict due to its variable presentation. We investigated the prognosticators of AM patients requiring hospitalization.

Methods and results: We conducted a multicenter observational study including 80 hospitalized AM patients. The primary endpoint was a composite of all-cause death, heart transplantation, and implantation of ventricular assist devices during the index hospitalization. Thirteen (16%) patients reached the endpoint. Longer QRS duration at admission independently predicted adverse outcomes, with an optimal cut-off of 130 ms.

Conclusions: Prolonged QRS duration at admission might predict in-hospital prognosis in AM patients regardless of whether or not it was fulminant.

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基线QRS持续时间延长可预测急性心肌炎患者的住院预后：多中心观察性研究

背景：急性心肌炎（AM）的临床表现多变，预后难以预测。我们调查了需要住院治疗的AM患者的预后因素。方法与结果：我们对80例住院AM患者进行了多中心观察性研究。主要终点是全因死亡、心脏移植和心室辅助装置植入的综合指标。13例（16%）患者达到终点。入院时较长的QRS持续时间独立预测不良结局，最佳截止时间为130 ms。结论：入院时较长的QRS持续时间可能预测AM患者的住院预后，无论其是否暴发性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Circulation reports

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