Correlation of CS and OCTA biomarkers in CSCR.

Romanian journal of ophthalmology Pub Date : 2025-10-01 DOI:10.22336/rjo.2025.86

Shaffi Chopra, Satya Prakash Singh, Gyanmani Pandey, Kamal Jeet Singh, Vinod Kumar Singh, Parul Singh

{"title":"Correlation of CS and OCTA biomarkers in CSCR.","authors":"Shaffi Chopra, Satya Prakash Singh, Gyanmani Pandey, Kamal Jeet Singh, Vinod Kumar Singh, Parul Singh","doi":"10.22336/rjo.2025.86","DOIUrl":null,"url":null,"abstract":"Objective aim: To identify Optical Coherence Tomography Angiography (OCTA) biomarkers in eyes with acute Central Serous Chorioretinopathy (CSCR) and assess their correlation with contrast sensitivity (CS).Methods: In this prospective observational study, 32 eyes of 30 patients with acute CSCR underwent OCTA, spectral-domain OCT, and fluorescein angiography. Contrast sensitivity was measured using the Pelli-Robson chart.Results: OCTA revealed three types of abnormalities: dark areas in all eyes, dark spots in five eyes (associated with serous retinal detachment and pigment epithelium detachment), and abnormal vessels in twelve eyes. Mean baseline CS was 1.42, which improved to 1.78 at six-month follow-up (p < 0.001).Discussion: Although OCTA abnormalities varied, the presence of persistent dark areas correlated with reduced contrast sensitivity, emphasizing that structural recovery does not equate to functional recovery.Conclusions: Although visual acuity normalized in most cases, persistent OCTA abnormalities and reduced CS highlighted ongoing visual quality impairment, indicating that anatomical recovery does not equate to full functional recovery.","PeriodicalId":94355,"journal":{"name":"Romanian journal of ophthalmology","volume":"69 4","pages":"562-566"},"PeriodicalIF":0.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065149/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian journal of ophthalmology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22336/rjo.2025.86","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective aim: To identify Optical Coherence Tomography Angiography (OCTA) biomarkers in eyes with acute Central Serous Chorioretinopathy (CSCR) and assess their correlation with contrast sensitivity (CS).

Methods: In this prospective observational study, 32 eyes of 30 patients with acute CSCR underwent OCTA, spectral-domain OCT, and fluorescein angiography. Contrast sensitivity was measured using the Pelli-Robson chart.

Results: OCTA revealed three types of abnormalities: dark areas in all eyes, dark spots in five eyes (associated with serous retinal detachment and pigment epithelium detachment), and abnormal vessels in twelve eyes. Mean baseline CS was 1.42, which improved to 1.78 at six-month follow-up (p < 0.001).

Discussion: Although OCTA abnormalities varied, the presence of persistent dark areas correlated with reduced contrast sensitivity, emphasizing that structural recovery does not equate to functional recovery.

Conclusions: Although visual acuity normalized in most cases, persistent OCTA abnormalities and reduced CS highlighted ongoing visual quality impairment, indicating that anatomical recovery does not equate to full functional recovery.

查看原文本刊更多论文

CSCR中CS与OCTA生物标志物的相关性研究。

目的：鉴别急性中枢性浆液性脉络膜视网膜病变（CSCR）眼的光学相干断层扫描血管造影（OCTA）生物标志物，并评估其与对比敏感度（CS）的相关性。方法：在这项前瞻性观察研究中，对30例急性CSCR患者的32只眼进行了OCTA、光谱域OCT和荧光素血管造影。对比敏感度采用Pelli-Robson图测量。结果：OCTA显示三种类型的异常：所有眼均见暗区，5眼见黑点（伴有浆液性视网膜脱离和色素上皮脱离），12眼见血管异常。平均基线CS为1.42,6个月随访时改善至1.78 （p < 0.001）。讨论：尽管OCTA异常各不相同，但持续暗区的存在与对比度敏感性降低相关，强调结构恢复不等于功能恢复。结论：虽然大多数病例的视力恢复正常，但持续的OCTA异常和CS减少突出了持续的视觉质量损害，表明解剖恢复不等于功能完全恢复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Romanian journal of ophthalmology

自引率

0.00%

发文量