Artificial Intelligence Across the PSMA Theranostic Continuum in Prostate Cancer.

Gowtham Murugesan, Stephen Moore, Anthony Chang, Brandon Mancini, Harshad Kulkarni
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Abstract

Prostate cancer is among the most common male malignancies worldwide, with recent advances in molecular imaging and targeted radiopharmaceutical therapy revolutionizing its management. PSMA has become a key theranostic target, enabling highly sensitive disease detection via PSMA PET/computed tomography (CT) imaging and effective treatment with PSMA-directed radioligand therapy. While PSMA theranostics are now standard in advanced prostate cancer care, increasing adoption strains specialist capacity and introduces variability in interpretation. Artificial intelligence (AI) and machine learning are poised to enhance this field by improving imaging accuracy, patient selection, treatment planning, and response monitoring.

人工智能在前列腺癌PSMA治疗中的应用。
前列腺癌是世界上最常见的男性恶性肿瘤之一,随着分子成像和靶向放射性药物治疗的最新进展,前列腺癌的治疗发生了革命性的变化。PSMA已成为一个关键的治疗靶点,可以通过PSMA PET/计算机断层扫描(CT)成像进行高灵敏度的疾病检测,并通过PSMA定向放射配体治疗进行有效治疗。虽然PSMA治疗现在是晚期前列腺癌治疗的标准,但越来越多的采用使专家能力紧张,并引入了解释的可变性。人工智能(AI)和机器学习将通过提高成像精度、患者选择、治疗计划和反应监测来加强这一领域。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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