{"title":"Teeth Health in Patients with Diabetes or Cardiovascular Disease: A Current and Updated Review.","authors":"Pardis Palizban, Zahra Tolou-Ghamari","doi":"10.2174/0115748871420951251211150458","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The recently published article reported that approximately 500 million individuals live with diabetes and cardiovascular disease (CVD) worldwide. It is well known that individuals with systemic diseases have a higher risk of developing dental problems. This review aims to update the association between dental problems in people with cardiovascular disease and diabetes.</p><p><strong>Methods: </strong>By searching PubMed, Web of Science, and Scopus, an evaluation of scientific texts (n=120) was conducted based on the subject of attention.</p><p><strong>Results: </strong>The strong association between periodontitis and atherosclerotic CVD suggested that patients with severe periodontitis are at an increased risk of developing CVD. In such conditions, dentists should be aware of dysfunctions associated with the saliva, which can individually increase the incidence of caries. The conditions related to the extraction sockets could be worsened due to inflammation, immune, endocrine, and neural aspects in patients with hyperglycemia. Periodontal disease is the sixth most common complication of diabetes. Diabetes mellitus is considered the most common cause of hospital admission. There is a higher chance of periodontal disease and tooth loss in patients with diabetes. Periodontitis could be associated with glycemic control.</p><p><strong>Discussion: </strong>Using subgingival instrumentation, accompanied by indigenous or total antimicrobials, and occasionally by surgical intervention to remove gum tissue when periodontitis is severe, restores glycaemic control in individuals with both periodontitis and diabetes. Oral dysbiosis could be associated with the aortic valve due to bacteria.</p><p><strong>Conclusion: </strong>Intervention and routine dental check-ups are recommended in patients with CVD and diabetes to reduce periodontal inflammation.</p>","PeriodicalId":21174,"journal":{"name":"Reviews on recent clinical trials","volume":" ","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews on recent clinical trials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115748871420951251211150458","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: The recently published article reported that approximately 500 million individuals live with diabetes and cardiovascular disease (CVD) worldwide. It is well known that individuals with systemic diseases have a higher risk of developing dental problems. This review aims to update the association between dental problems in people with cardiovascular disease and diabetes.
Methods: By searching PubMed, Web of Science, and Scopus, an evaluation of scientific texts (n=120) was conducted based on the subject of attention.
Results: The strong association between periodontitis and atherosclerotic CVD suggested that patients with severe periodontitis are at an increased risk of developing CVD. In such conditions, dentists should be aware of dysfunctions associated with the saliva, which can individually increase the incidence of caries. The conditions related to the extraction sockets could be worsened due to inflammation, immune, endocrine, and neural aspects in patients with hyperglycemia. Periodontal disease is the sixth most common complication of diabetes. Diabetes mellitus is considered the most common cause of hospital admission. There is a higher chance of periodontal disease and tooth loss in patients with diabetes. Periodontitis could be associated with glycemic control.
Discussion: Using subgingival instrumentation, accompanied by indigenous or total antimicrobials, and occasionally by surgical intervention to remove gum tissue when periodontitis is severe, restores glycaemic control in individuals with both periodontitis and diabetes. Oral dysbiosis could be associated with the aortic valve due to bacteria.
Conclusion: Intervention and routine dental check-ups are recommended in patients with CVD and diabetes to reduce periodontal inflammation.
导读：最近发表的一篇文章报道，全世界约有5亿人患有糖尿病和心血管疾病（CVD）。众所周知，患有全身性疾病的人患牙齿问题的风险更高。这篇综述旨在更新心血管疾病和糖尿病患者牙齿问题之间的关系。方法：通过检索PubMed、Web of Science和Scopus，根据关注的主题对120篇科学文献进行评价。结果：牙周炎和动脉粥样硬化性心血管疾病之间的密切联系表明，严重牙周炎患者发生心血管疾病的风险增加。在这种情况下，牙医应该意识到与唾液相关的功能障碍，这可能单独增加龋齿的发病率。由于炎症、免疫、内分泌、神经等方面的原因，高血糖患者拔牙窝相关的情况可能会恶化。牙周病是糖尿病的第六大常见并发症。糖尿病被认为是最常见的住院原因。糖尿病患者患牙周病和牙齿脱落的几率更高。牙周炎可能与血糖控制有关。讨论：在牙周炎严重时，使用牙龈下器械，同时使用本地或全部抗菌剂，偶尔通过手术干预去除牙龈组织，可以恢复牙周炎和糖尿病患者的血糖控制。口腔生态失调可能与细菌引起的主动脉瓣病变有关。结论：心血管疾病合并糖尿病患者应采取干预措施并进行常规口腔检查，以减少牙周炎症。
期刊介绍：
Reviews on Recent Clinical Trials publishes frontier reviews on recent clinical trials of major importance. The journal"s aim is to publish the highest quality review articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development and therapeutics. The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.
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