Fungating Mass of the Glans Penis: A Case Report and Discussion on Penile Squamous Cell Carcinoma.

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL

Journal of investigative medicine high impact case reports Pub Date : 2026-01-01 Epub Date: 2026-04-13 DOI:10.1177/23247096251381563

Dominic M Collins, Alex Marvin Simpkins, John Diks, Dale Robertson

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引用次数: 0

Abstract

Penile squamous cell carcinoma (PSCC) is a rare presentation in the United States and Europe, accounting for only 1% of male malignancies. Most commonly due to human papilloma virus (HPV), PSCC has an insidious onset, often ignored by patients until functional impairments are present. This report outlines an interesting presentation of penile squamous cell carcinoma while focusing on current developments in the prognosis and treatment of PSCC. We present the case of a 68-year-old male who presented with a 5 cm fungating mass of the glans penis after emergent care following a stroke. Visual inspection revealed a large mass of the glans penis which had completely obliterated the urethral meatus. A partial penectomy and urethrostomy were performed. Surgical excision revealed a unifocal moderately differentiated (G2) squamous cell carcinoma, with immunohistochemical staining demonstrating p16 positivity, consistent with HPV-associated etiology. This case highlights the importance of individualized treatment regimens and prognostic determination for optimal patient outcomes.

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阴茎龟头真菌团块一例报告及对阴茎鳞状细胞癌的讨论。

阴茎鳞状细胞癌（PSCC）在美国和欧洲是一种罕见的表现，仅占男性恶性肿瘤的1%。PSCC通常由人乳头瘤病毒（HPV）引起，发病隐匿，通常被患者忽视，直到出现功能障碍。本报告概述了阴茎鳞状细胞癌的一个有趣的介绍，同时重点介绍了PSCC的预后和治疗的最新进展。我们提出的情况下，68岁的男性谁提出了一个5厘米的真菌团的阴茎头后紧急护理后中风。目视检查发现一大块阴茎龟头，完全覆盖了尿道道。行部分阴茎切除术及尿道造口术。手术切除显示为单灶中分化（G2）鳞状细胞癌，免疫组化染色显示p16阳性，与hpv相关病因一致。该病例强调了个性化治疗方案和预后确定对最佳患者结果的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of investigative medicine high impact case reports MEDICINE, GENERAL & INTERNAL-

CiteScore

1.90

自引率

0.00%

发文量

165

审稿时长

12 weeks

期刊介绍： The AFMR is committed to enhancing the training and career development of our members and to furthering its mission to facilitate the conduct of research to improve medical care. Case reports represent an important avenue for trainees (interns, residents, and fellows) and early-stage faculty to demonstrate productive, scholarly activity.