Long-standing, multifocal Tuberculosis verrucosa cutis: Undiagnosed for 40 years

IF 0.9 Q4 INFECTIOUS DISEASES

IDCases Pub Date : 2026-01-01 Epub Date: 2026-04-06 DOI:10.1016/j.idcr.2026.e02568

Seblewengel Maru Wubalem , Helina Melis Kefetew , Saada Yasin Abduselam , Shemsu Abraham Hussien

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Abstract

Background

Tuberculosis (TB) is a chronic infectious disease primarily affecting the lungs, with extrapulmonary TB comprising 20% of cases. Among these, cutaneous TB (CTB) accounts for 1–2%, often overlooked due to its rarity and varied presentations. This report highlights an unusual case of Tuberculosis verrucosa cutis (TVC)

Case presentation

A 60-year-old male, presented with non-healing skin lesion that remained undiagnosed for 40 years. The lesion, which involved multiple areas of the body, exhibited large annular plaques with indurated edges and atrophic scars. Diagnosis was made through a detailed clinical history and examination, confirmed by fine-needle aspiration cytology (FNAC), which revealed necrotizing granulomatous inflammation. The patient responded well to anti-TB treatment, showing significant improvement within two months.

Conclusion

This case underscores the importance of clinical suspicion in diagnosing CTB, particularly in endemic regions, and suggests that FNAC is a valuable diagnostic tool in resource-limited settings.

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长期多灶性皮肤疣状结核：40年未确诊

结核病（TB）是一种主要影响肺部的慢性传染病，肺外结核占病例的20%。其中，皮肤结核（CTB）占1-2%，由于其罕见和多样的表现而经常被忽视。本文报告一例罕见的皮肤疣状结核（TVC）病例：一名60岁男性，皮肤病变未愈合，40年未确诊。病变涉及身体多个区域，表现为大的环形斑块，边缘硬化和萎缩性疤痕。通过详细的临床病史和检查做出诊断，细针穿刺细胞学（FNAC）证实，显示坏死性肉芽肿性炎症。患者对抗结核治疗反应良好，在两个月内表现出显著改善。结论该病例强调了临床怀疑对诊断CTB的重要性，特别是在流行地区，并提示FNAC在资源有限的情况下是一种有价值的诊断工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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