Intraindividual comparison of 3-T and 5-T gadoxetic acid-enhanced MRI for evaluating HCC: initial findings

IF 2.3 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Abdominal Radiology Pub Date : 2026-04-10 DOI:10.1007/s00261-026-05500-6

Shaopeng Li, Shuhang Liang, Mengqiu Liu, Xudan Chen, Dawei Yin, Zhichao Feng, Runyu Tang, Xiaopeng Song, Peng Wang, Ying Liu, Lianxin Liu

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引用次数: 0

Abstract

Background

We aimed to evaluate the utility of 5-T Gadolinium-ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) by intraindividual comparison with 3-T MRI, with a focus on the image quality and diagnosis of hepatocellular carcinoma (HCC).

Methods

We prospectively enrolled 41 patients with suspected HCC who underwent dynamic Gd-EOB-DTPA-enhanced MRI using both 5-T and 3-T scanners. Artificial intelligence-assisted compressed sensing (ACS) and parallel imaging (PI) were both used for hepatobiliary phase (HBP) imaging at 5-T. Two radiologists performed qualitative and quantitative assessments of image quality and evaluations of imaging features. Wilcoxon signed-rank, paired χ², and Cochran Q tests as well as intraclass correlation coefficients and the Cohen κ value were used.

Results

All subjective image quality scores ranged from good to excellent. The subjective scores of contrast-enhanced phases for 5-T images were higher than those for 3-T images (all p < 0.05), except for image artifacts. For diffusion-weighted imaging (DWI), the subjective scores of the clarity of the lesion margins on 5-T images were higher than those on 3-T images (p = 0.021). Quantitative measures were also greater for 5-T images (all p < 0.05). For DWI, the contrast ratio (CR) at 5-T was greater (p < 0.05). Subjective and quantitative assessments of HBP imaging were higher with ACS (all p < 0.05). The detection rate of enhancing capsule was greater for 5-T images (p = 0.016), as was the rate of peritumoral hypointensity on the HBP images at 5-T using ACS (p = 0.015).

Conclusions

Compared with 3-T MRI, liver dynamic Gd-EOB-DTPA-enhanced 5-T MRI demonstrated superior image quality for contrast-enhanced phases and greater sensitivity in detecting enhancing capsule in HCC. The integration of 5-T MRI and ACS technology has the potential to further improve image quality and the assessment of imaging features.

Relevance statement

Gd-EOB-DTPA-enhanced 5-T MRI provides promising potential for accurate HCC evaluation.

查看原文本刊更多论文

3-T和5-T加多辛酸增强MRI评估HCC的个体比较：初步发现。

背景：我们旨在通过与3-T MRI的个体内比较，评估5-T钆-乙氧基苄基二乙烯三胺五乙酸（Gd-EOB-DTPA）增强磁共振成像（MRI）的实用性，重点关注肝细胞癌（HCC）的图像质量和诊断。方法：我们前瞻性地招募了41例疑似HCC患者，他们使用5-T和3-T扫描仪进行动态gd - eob - dtpa增强MRI。人工智能辅助压缩感知（ACS）和并行成像（PI）均用于5-T肝胆期（HBP）成像。两名放射科医生对图像质量和成像特征进行定性和定量评估。采用Wilcoxon符号秩检验、配对χ2检验、Cochran Q检验以及类内相关系数和Cohen κ值。结果：主观图像质量评分从好到优。结论：与3-T MRI相比，肝脏动态gd - eob - dtpa增强5-T MRI对对比增强期的图像质量更好，对HCC增强囊的检测灵敏度更高。5-T MRI与ACS技术的结合有可能进一步提高图像质量和影像学特征的评估。相关性声明：gd - eob - dtpa增强的5-T MRI为准确评估HCC提供了有希望的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits