Prevalence of depression and association with quality-of-life among oncology patients at Princess Marina Hospital, Botswana: A cross-sectional study.

IF 1.3 4区医学 Q4 PSYCHIATRY

South African Journal of Psychiatry Pub Date : 2026-03-03 eCollection Date: 2026-01-01 DOI:10.4102/sajpsychiatry.v32i0.2586

Swetha B Jammalamadugu, Rebecca Luckett, Philip Opondo

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引用次数: 0

Abstract

Background: Depression significantly impacts cancer patients globally, complicating treatment outcomes by negatively affecting quality-of-life (QOL), self-care and treatment adherence. However, little is known about the prevalence of depression and its effects on QOL among cancer patients in Botswana.

Aim: This study aimed to assess the prevalence of depression and its relationship with QOL among cancer patients at Princess Marina Hospital's oncology unit.

Setting: Patients seen at the oncology unit of Princess Marina Hospital, Botswana's largest tertiary referral hospital.

Methods: A cross-sectional study was conducted from February 2023 to August 2024. The sample size was 302. Socio-demographic data were collected using a researcher-designed questionnaire. Depression was assessed using the PHQ-9, with a score of 9 or higher indicating depression, and QOL was measured using the WHOQOL-BREF.

Results: The prevalence of depression was 35.8% (95% confidence interval [CI]: 30.3%, 41.5%). Patients with depression had a higher mean pain score (6 vs. 4, p < 0.001) and poorer QOL across all domains: physical health (40.9 vs. 59.7, p < 0.001), psychological health (52.3 vs. 69.3, p < 0.001), social relationships (49.0 vs. 68.3, p < 0.001) and environmental health (48.1 vs. 58.8, p < 0.001). A new diagnosis of cancer was associated with an increased risk of depression (p = 0.03).

Conclusion: The prevalence of depression among cancer patients is high in Botswana, and it is associated with poorer QOL, highlighting a significant public health concern.

Contribution: Treatment of depression in this group of patients, along with pain management, may be crucial in improving their QOL.

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博茨瓦纳Marina公主医院肿瘤患者的抑郁患病率及其与生活质量的关系：一项横断面研究。

背景：抑郁症对全球癌症患者有显著影响，通过负面影响生活质量（QOL）、自我护理和治疗依从性，使治疗结果复杂化。然而，人们对博茨瓦纳癌症患者中抑郁症的患病率及其对生活质量的影响知之甚少。目的：探讨滨海公主医院肿瘤科肿瘤患者的抑郁患病率及其与生活质量的关系。环境：博茨瓦纳最大的三级转诊医院Marina公主医院肿瘤科的病人。方法：于2023年2月至2024年8月进行横断面研究。样本量为302。使用研究者设计的问卷收集社会人口统计数据。采用PHQ-9量表评定抑郁程度，9分及以上为抑郁，采用WHOQOL-BREF量表测定生活质量。结果：抑郁症患病率为35.8%（95%可信区间[CI]: 30.3%, 41.5%）。抑郁症患者在所有领域的平均疼痛评分较高（6比4，p < 0.001），生活质量较差：身体健康（40.9比59.7,p < 0.001）、心理健康（52.3比69.3,p < 0.001）、社会关系（49.0比68.3,p < 0.001）和环境健康（48.1比58.8,p < 0.001）。新诊断的癌症与抑郁风险增加相关（p = 0.03）。结论：博茨瓦纳癌症患者中抑郁症的患病率很高，并且与较差的生活质量有关，这突出了一个重要的公共卫生问题。贡献：在这组患者中治疗抑郁症，以及疼痛管理，可能对改善他们的生活质量至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

South African Journal of Psychiatry 医学-精神病学

CiteScore

1.60

自引率

10.00%

发文量

审稿时长

>12 weeks

期刊介绍： The journal is the leading psychiatric journal of Africa. It provides open-access scholarly reading for psychiatrists, clinical psychologists and all with an interest in mental health. It carries empirical and conceptual research articles, reviews, editorials, and scientific letters related to psychiatry. It publishes work from various places in the world, and makes special provision for the interests of Africa. It seeks to serve its readership and researchers with the most topical content in psychiatry for clinical practice and academic pursuits, including work in the subspecialty areas of psychiatry.