Geospatial analysis of COVID-19 vaccine access in Kenya: the interplay of travel time, perceived availability, and vaccine uptake.

IF 4.3 3区 医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Jiashuo Sun, Yanjia Cao, Karen Ann Grépin, Tianyu Li, Huanfa Chen, Qunshan Zhao, Primus Che Chi
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Abstract

Background: COVID-19 vaccines have reduced severe illness and mortality, yet inequitable distribution delayed rollout in many low- and middle-income countries (LMICs), including Kenya, where only 36% of adults were fully vaccinated by October 2022. While sociodemographic and attitudinal determinants of uptake are well documented, role of geographic access remain underexplored at individual level. This study assessed population coverage by travel time to COVID-19 vaccination sites in Kenya and examined how travel time was associated with perceived vaccine availability and vaccine uptake.

Methods: We conducted a secondary analysis of cross-sectional data from Round 3 (October-December 2021) of the COVID-19 Gendered Risks, Impact, and Response Survey. Vaccination site locations were obtained from the Kenyan Ministry of Health. Travel times from constituency population-weighted centroids to the nearest site were estimated using a cost-path distance algorithm in AccessMod. Two binary outcomes were analysed: perceived vaccine availability and vaccine uptake. Logistic regression with restricted cubic splines modelled associations with travel time in the full sample and a restricted sample excluding respondents who reported vaccines as 'unavailable' despite modelled travel time <15 minutes.

Results: Nationally, 55% of the population lived within 30 minutes of a vaccination site, 69% within 60 minutes, and 21.6% more than 120 minutes away, with shorter travel times concentrated around major cities and longer times in eastern and northern Kenya. In the full analytic sample, travel time was not significantly associated with perceived availability or uptake. In the restricted sample, longer travel time showed strong, nonlinear associations with lower perceived availability and uptake.

Conclusions: Geographic barriers, captured by modelled travel time, are important determinants of perceived vaccine availability and uptake in Kenya. Combining high-resolution geospatial modelling with individual-level data can guide expansion of vaccination services to improve vaccine equity and preparedness for future health emergencies in Kenya and similar LMICs.

肯尼亚COVID-19疫苗获取的地理空间分析:旅行时间、感知可获得性和疫苗摄取的相互作用
背景:COVID-19疫苗减少了严重疾病和死亡率,但分配不公平推迟了许多低收入和中等收入国家(LMICs)的疫苗推广,包括肯尼亚,到2022年10月,肯尼亚只有36%的成年人接种了完全疫苗。虽然社会人口统计学和态度上的决定因素已经得到了很好的记录,但地理获取的作用在个人层面上仍然没有得到充分的探讨。本研究根据前往肯尼亚COVID-19疫苗接种点的旅行时间评估了人口覆盖率,并研究了旅行时间与感知疫苗可获得性和疫苗吸取量之间的关系。方法:我们对2019冠状病毒病性别风险、影响和应对调查第三轮(2021年10月至12月)的横断面数据进行了二次分析。疫苗接种地点已从肯尼亚卫生部获得。使用AccessMod中的成本路径距离算法估计从选区人口加权质心到最近站点的旅行时间。分析了两种二元结果:感知疫苗可得性和疫苗摄取。限制三次样条的Logistic回归模拟了整个样本和排除了尽管模拟了旅行时间但仍报告疫苗“不可用”的受限制样本中旅行时间的关联:在全国范围内,55%的人口居住在距离疫苗接种地点30分钟内,69%在60分钟内,21.6%居住在120分钟以外,旅行时间较短,集中在主要城市周围,而肯尼亚东部和北部的旅行时间较长。在完整的分析样本中,旅行时间与感知到的可用性或摄取没有显着关联。在有限的样本中,较长的旅行时间与较低的感知可用性和摄取表现出强烈的非线性关联。结论:通过模拟旅行时间捕捉到的地理障碍是肯尼亚疫苗可获得性和吸收率的重要决定因素。将高分辨率地理空间模型与个人层面的数据相结合,可以指导扩大疫苗接种服务,以改善疫苗公平性,并为肯尼亚和类似的中低收入国家未来的突发卫生事件做好准备。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Global Health
Journal of Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -
CiteScore
6.10
自引率
2.80%
发文量
240
审稿时长
6 weeks
期刊介绍: Journal of Global Health is a peer-reviewed journal published by the Edinburgh University Global Health Society, a not-for-profit organization registered in the UK. We publish editorials, news, viewpoints, original research and review articles in two issues per year.
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