Pediatric infection imaging focusing on FDG PET/CT: Techniques, safety, and indications

IF 6.6 2区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Seminars in nuclear medicine Pub Date : 2026-05-01 Epub Date: 2026-04-09 DOI:10.1053/j.semnuclmed.2026.03.011
Murat Alp Oztek , Barry L. Shulkin , Marguerite T. Parisi
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引用次数: 0

Abstract

Scintigraphic imaging remains pivotal in the evaluation of children with infectious and inflammatory diseases. Data acquired over the last several decades has demonstrated high efficacy of 2-[18F]Fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) for evaluation of infection; efficacy which far surpasses that of conventional agents like 67Gallium-citrate, labeled white blood cells and bone scintigraphy with 99mtechnetium methylene diphosphonate. While this manuscript provides an overview of scintigraphy in pediatric infection imaging, the primary focus is on the use of FDG-PET/CT for this indication. Safety concerns, recent advances in scanner technology and indications for FDG-PET/CT in infection are addressed.
Scintigraphic imaging remains pivotal in the evaluation of children with infectious and inflammatory diseases. Data acquired over the last several decades has demonstrated high efficacy of 2-[18F]Fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography (FDG-PET/CT) for evaluation of infection; efficacy which far surpasses that of conventional agents like 67Gallium-citrate, labeled white blood cells and bone scintigraphy with 99mtechnetium methylene diphosphonate. While this manuscript provides an overview of scintigraphy in pediatric infection imaging, the primary focus is on the use of FDG-PET/CT for this indication. Safety concerns, recent advances in scanner technology and indications for FDG-PET/CT in infection are addressed.
以FDG PET/CT为重点的儿科感染成像:技术、安全性和适应症。
闪烁成像仍然是评估儿童感染性和炎症性疾病的关键。过去几十年获得的数据表明,2-[18F]氟-2-脱氧-d-葡萄糖正电子发射断层扫描/计算机断层扫描(FDG-PET/CT)用于评估感染的有效性很高;它的功效远远超过了传统的药物,如67柠檬酸镓、99亚甲基二膦酸锝标记的白细胞和骨显像。虽然这篇文章概述了儿童感染成像中的闪烁成像,但主要的重点是FDG-PET/CT在这方面的应用。安全问题,扫描技术的最新进展和FDG-PET/CT在感染中的适应症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Seminars in nuclear medicine
Seminars in nuclear medicine 医学-核医学
CiteScore
9.80
自引率
6.10%
发文量
86
审稿时长
14 days
期刊介绍: Seminars in Nuclear Medicine is the leading review journal in nuclear medicine. Each issue brings you expert reviews and commentary on a single topic as selected by the Editors. The journal contains extensive coverage of the field of nuclear medicine, including PET, SPECT, and other molecular imaging studies, and related imaging studies. Full-color illustrations are used throughout to highlight important findings. Seminars is included in PubMed/Medline, Thomson/ISI, and other major scientific indexes.
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