Modelling the peripheral blood count dynamics in workers externally exposed to ionizing radiation during prolonged periods.

IF 0.8 4区 环境科学与生态学 Q4 ENVIRONMENTAL SCIENCES
Sergey V Osovets, Evgenia S Grigoryeva, Tamara V Azizova
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引用次数: 0

Abstract

The aim of the study was to model the dynamics of the peripheral blood count (platelets) in Russian nuclear workers chronically exposed to external gamma rays. Workers were divided in three groups depending on the total dose absorbed in bone marrow: <1.0 Gy, 1.0 to 2.0 Gy, ≥2.0 Gy. Factors such as the total dose, dose rate and duration of employment were considered as determinants of the platelet count dynamics. A dynamic regression model revealed statistically significant dose-response relationship in all study groups, while, in contrast, the analytical model fitted the data well only in the third group. The proposed method allows for the quantitative assessment of the time-dependent changes in the parameters of the peripheral blood relative to the individual initial level. This is critically important in case of chronic occupational exposure when cumulative dose increases with the increase in the duration of work with the ionizing radiation sources.

模拟长时间暴露于外部电离辐射的工人外周血计数动态。
该研究的目的是模拟长期暴露于外部伽马射线的俄罗斯核工人外周血计数(血小板)的动态。工作人员根据骨髓吸收的总剂量分为三组:
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Radiation protection dosimetry
Radiation protection dosimetry 环境科学-公共卫生、环境卫生与职业卫生
CiteScore
1.40
自引率
10.00%
发文量
223
审稿时长
6-12 weeks
期刊介绍: Radiation Protection Dosimetry covers all aspects of personal and environmental dosimetry and monitoring, for both ionising and non-ionising radiations. This includes biological aspects, physical concepts, biophysical dosimetry, external and internal personal dosimetry and monitoring, environmental and workplace monitoring, accident dosimetry, and dosimetry related to the protection of patients. Particular emphasis is placed on papers covering the fundamentals of dosimetry; units, radiation quantities and conversion factors. Papers covering archaeological dating are included only if the fundamental measurement method or technique, such as thermoluminescence, has direct application to personal dosimetry measurements. Papers covering the dosimetric aspects of radon or other naturally occurring radioactive materials and low level radiation are included. Animal experiments and ecological sample measurements are not included unless there is a significant relevant content reason.
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