IgE elevation temporally associated with dermal Glufosinate ammonium exposure in an elderly patient: A case report from Vietnam.

IF 2.1 Q3 ALLERGY

Asia Pacific Allergy Pub Date : 2026-04-01 Epub Date: 2025-11-04 DOI:10.5415/apallergy.0000000000000241

Dang Duc Nguyen, Nguyen Hong Anh Lam, Dang Bach Nguyen

引用次数: 0

Abstract

Glufosinate ammonium (GLA) is a nonselective herbicide of the phosphinic acid group, which is widely used in agriculture. Dermatologic toxicity has been rarely reported, especially in the elderly. We present the case of a 94-year-old female patient who developed irritant contact dermatitis and paresthesia after using her feet to stir 20 vials of Glufosinate ammonium herbicide in water. The patient presented with pruritus, numbness of the extremities, and a very high immunoglobulin E (IgE) elevation (855.5 IU/mL), which gradually decreased over time. This is the first report in Vietnam describing a delayed systemic IgE elevation due to dermal exposure to Glufosinate ammonium in a very elderly person.

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IgE升高与老年患者皮肤草铵膦暴露的临时性相关性：越南一例报告。

草甘膦铵（GLA）是一种非选择性的膦酸类除草剂，在农业上有着广泛的应用。皮肤毒性很少报道，特别是在老年人中。我们提出的情况下，94岁的女性患者谁发展刺激性接触性皮炎和感觉异常后，用她的脚搅拌20瓶草甘膦铵除草剂在水中。患者表现为瘙痒，四肢麻木，免疫球蛋白E （IgE）升高非常高（855.5 IU/mL），随时间逐渐降低。这是越南首次报道一名老年人皮肤暴露于草铵膦引起的迟发性全身IgE升高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asia Pacific Allergy ALLERGY-

CiteScore

2.50

自引率

5.90%

发文量

期刊介绍： Asia Pacific Allergy (AP Allergy) is the official journal of the Asia Pacific Association of Allergy, Asthma and Clinical Immunology (APAAACI). Although the primary aim of the journal is to promote communication between Asia Pacific scientists who are interested in allergy, asthma, and clinical immunology including immunodeficiency, the journal is intended to be available worldwide. To enable scientists and clinicians from emerging societies appreciate the scope and intent of the journal, early issues will contain more educational review material. For better communication and understanding, it will include rational concepts related to the diagnosis and management of asthma and other immunological conditions. Over time, the journal will increase the number of original research papers to become the foremost citation journal for allergy and clinical immunology information of the Asia Pacific in the future.