Automated paraffin embedding of tissue samples significantly reduces overall workflow time in routine pathology practice.

IF 2.9 Q1 PATHOLOGY
Alessandro Gambella, Laura Zito, Cristina Bottaro, Michele Paudice, Giulia Tacchino, Viviana Accorrà, Claudio Piccione, Martina Terrile, Anna Silvana Bevere, Barbara Massa, Silvia Bozzano, Federica Grillo, Luca Mastracci
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引用次数: 0

Abstract

Objective: Automated paraffin embedding (AE) offers a solution to the operator-dependent variability and time demands manual embedding (ME), but comparative data are limited.

Methods: We quantitatively assessed AE versus ME using 186 endoscopic biopsies, 106 needle biopsies, and 62 transurethral resections, recording the time (seconds, s) required for preparation, embedding, trimming, and sectioning.

Results: AE substantially reduced embedding time (5 s for all sample types) compared with ME (43 s for endoscopic biopsies, 66.5 s for needle biopsies, and 105 s for transurethral samples), and it allowed laboratory technicians to perform other tasks concurrently. AE also shortened total time: 150.2 s (AE) vs. 250.4 s (ME) for endoscopic biopsies, 176.9 s (AE) vs. 324.2 s (ME) for needle biopsies, and 149.5 s (AE) vs. 335 s (ME) for transurethral resections.

Conclusions: These real-world data provide quantitative evidence of AE-related time savings in daily routine activity, supporting its role in workflow automation and standardization in pathology units.

组织样品的自动石蜡包埋显着减少了常规病理实践的整体工作流程时间。
目的:自动石蜡包埋(AE)为人工包埋(ME)提供了一种解决操作者依赖性变异和时间要求的方法,但可比较的数据有限。方法:我们通过186例内镜活检、106例穿刺活检和62例经尿道切除术定量评估AE与ME,记录准备、包埋、修剪和切片所需的时间(秒,s)。结果:声发射比ME(内镜活检43 s,针刺活检66.5 s,经尿道活检105 s)大大缩短了包埋时间(所有样品类型均为5 s),并使实验室技术人员能够同时执行其他任务。AE也缩短了总时间:内窥镜活检150.2 s (AE) vs 250.4 s (ME),针刺活检176.9 s (AE) vs 324.2 s (ME),经尿道切除术149.5 s (AE) vs 335 s (ME)。结论:这些真实世界的数据提供了ae在日常活动中节省时间的定量证据,支持其在病理单位工作流程自动化和标准化中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
PATHOLOGICA
PATHOLOGICA PATHOLOGY-
CiteScore
5.90
自引率
5.70%
发文量
108
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