From diversity to function: microbiome precision in RCC

IF 13.6 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2026-04-08 DOI:10.1038/s41585-026-01140-z

Antonio Ocejo, Ritesh R. Kotecha, Martin H. Voss

引用次数: 0

Abstract

Evidence suggests that the gut microbiome is a key regulator of systemic immunity influencing efficacy and tolerance of immune checkpoint inhibitors. Results of two trials of faecal microbiota transplantation in metastatic renal cell carcinoma provide new insights into microbiome modulation in cancer therapy.

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从多样性到功能：RCC中微生物组的精确性。

有证据表明，肠道微生物组是影响免疫检查点抑制剂疗效和耐受性的全身免疫的关键调节因子。两项转移性肾细胞癌粪便微生物群移植试验的结果为癌症治疗中的微生物群调节提供了新的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.