{"title":"Accuracy of Intraocular Lens Power Calculation Formulas Using Total Keratometry in Eyes With Previous Radial Keratotomy.","authors":"Yuxing Zheng, Haowen Lin, Xiaohang Xie, Xiaozhang Qiu, Xuhua Tan, Jiaqing Zhang, Lixia Luo","doi":"10.3928/1081597X-20260112-07","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the performance of intraocular lens (IOL) power calculation using standard keratometry (SK) and total keratometry (TK) in eyes after radial keratotomy (RK) surgery.</p><p><strong>Methods: </strong>A retrospective, consecutive case series study included 49 patients with cataract (65 eyes) after RK. All implanted IOLs were monofocal in-the-bag lenses. Formulas using SK included American Society of Cataract and Refractive Surgery (ASCRS) average, Barrett True K, double-K modified Holladay 1 formula (DK-Holladay), Emmetropia Verifying Optical formula 2.0 (EVO 2.0), Holladay 1, Holladay 2, PEARL-DGS, and LISA formula for patients with cataract and prior myopic refractive surgery (LISA-MRS). Formulas using TK included Barrett True K-TK, EVO 2.0-TK, Holladay 2-TK, and LISA-MRS-TK. Holladay formulas used both Wang-Koch (Holladay-WK) and Holladay axial length (Holladay-AL) adjustment. The mean prediction error (PE), mean absolute PE (MAE), median absolute error (MedAE), root mean square absolute error (RMSAE), and the percentage of eyes within ±0.25, ±0.50, ±0.75, and ±1.00 diopters (D) of PE were evaluated.</p><p><strong>Results: </strong>In formulas using SK, the LISA-MRS formula exhibited the lowest MAE (0.71 D), lowest MedAE (0.52 D), and highest percentage of eyes within ±0.50 D of PE (49.23%). In formulas using TK, the LISA-MRS-TK formula exhibited the lowest MAE (0.78 D), lowest MedAE (0.48 D), and highest percentage of eyes within ±0.50 D of PE (52.63%). Using TK instead of SK significantly reduced the PE of both the Holladay 2 and LISA-MRS formulas. When AL was 30 mm or greater, the Holladay 1-AL formula exhibited the lowest MAE (0.68 D), lowest MedAE (0.32 D), and the highest percentage of eyes within ±0.50 D of PE (59.09%).</p><p><strong>Conclusions: </strong>In post-RK eyes, the LISA-MRS formula displayed the highest prediction accuracy. TK could improve the prediction accuracy of the Holladay 2 and LISA-MRS formulas.</p>","PeriodicalId":16951,"journal":{"name":"Journal of refractive surgery","volume":"42 4","pages":"e318-e326"},"PeriodicalIF":3.0000,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of refractive surgery","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3928/1081597X-20260112-07","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To evaluate the performance of intraocular lens (IOL) power calculation using standard keratometry (SK) and total keratometry (TK) in eyes after radial keratotomy (RK) surgery.
Methods: A retrospective, consecutive case series study included 49 patients with cataract (65 eyes) after RK. All implanted IOLs were monofocal in-the-bag lenses. Formulas using SK included American Society of Cataract and Refractive Surgery (ASCRS) average, Barrett True K, double-K modified Holladay 1 formula (DK-Holladay), Emmetropia Verifying Optical formula 2.0 (EVO 2.0), Holladay 1, Holladay 2, PEARL-DGS, and LISA formula for patients with cataract and prior myopic refractive surgery (LISA-MRS). Formulas using TK included Barrett True K-TK, EVO 2.0-TK, Holladay 2-TK, and LISA-MRS-TK. Holladay formulas used both Wang-Koch (Holladay-WK) and Holladay axial length (Holladay-AL) adjustment. The mean prediction error (PE), mean absolute PE (MAE), median absolute error (MedAE), root mean square absolute error (RMSAE), and the percentage of eyes within ±0.25, ±0.50, ±0.75, and ±1.00 diopters (D) of PE were evaluated.
Results: In formulas using SK, the LISA-MRS formula exhibited the lowest MAE (0.71 D), lowest MedAE (0.52 D), and highest percentage of eyes within ±0.50 D of PE (49.23%). In formulas using TK, the LISA-MRS-TK formula exhibited the lowest MAE (0.78 D), lowest MedAE (0.48 D), and highest percentage of eyes within ±0.50 D of PE (52.63%). Using TK instead of SK significantly reduced the PE of both the Holladay 2 and LISA-MRS formulas. When AL was 30 mm or greater, the Holladay 1-AL formula exhibited the lowest MAE (0.68 D), lowest MedAE (0.32 D), and the highest percentage of eyes within ±0.50 D of PE (59.09%).
Conclusions: In post-RK eyes, the LISA-MRS formula displayed the highest prediction accuracy. TK could improve the prediction accuracy of the Holladay 2 and LISA-MRS formulas.
期刊介绍:
The Journal of Refractive Surgery, the official journal of the International Society of Refractive Surgery, a partner of the American Academy of Ophthalmology, has been a monthly peer-reviewed forum for original research, review, and evaluation of refractive and lens-based surgical procedures for more than 30 years. Practical, clinically valuable articles provide readers with the most up-to-date information regarding advances in the field of refractive surgery. Begin to explore the Journal and all of its great benefits such as:
• Columns including “Translational Science,” “Surgical Techniques,” and “Biomechanics”
• Supplemental videos and materials available for many articles
• Access to current articles, as well as several years of archived content
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