The outcome of pre-renal transplant bladder cycling in patients with defunctionalized bladder.

IF 1.2 Q3 UROLOGY & NEPHROLOGY

Arab Journal of Urology Pub Date : 2025-09-12 eCollection Date: 2026-01-01 DOI:10.1080/20905998.2025.2560262

M Esmat, Ahmed Higazy, Mohamed Shaker, Ahmed Radwan, Mohamed Kandil

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引用次数: 0

Abstract

Objectives: To evaluate the effectiveness of programmed bladder cycling (PBC) prior to transplantation in patients with defunctionalized bladders (DB).

Methods: This prospective cohort study included RT candidates with DB. Eligible patients underwent pre-transplant PBC, and urodynamic parameters were assessed before and after the intervention. The primary outcome was the improvement in bladder capacity. Secondary outcomes included voiding parameters, and perioperative urological complications.

Results: 23 patients underwent PBC for a maximum of 6 months duration. Of these, 20 (86%) patients achieved the targeted bladder capacity of ≥ 250 ml. Median bladder capacity significantly increased from 147.5 mL (IQR 128.8-155) pre-PBC to 265 mL (IQR 253.8-286.3) post-PBC (p < 0.001). Median bladder compliance improved from 12 mL/cmH₂O (IQR 9-14) to 25 mL/cmH₂O (IQR 20.8-30) (p < 0.001). Post-RT, bladder capacity further increased to 314 mL (IQR 310-325) at 3 months and 376 mL (IQR 360-393.5) at 6 months (p < 0.001). Only one patient (5%) developed febrile UTI requiring readmission.

Conclusion: PBC is a simple and effective outpatient intervention that significantly improves bladder capacity and compliance in patients with DB and probably decreases complications that may occur during and after renal transplantation.

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膀胱功能失能患者肾移植前膀胱循环的结果。

目的：评价膀胱功能失能（DB）患者移植前程序性膀胱循环（PBC）的有效性。方法：该前瞻性队列研究纳入了DB的RT候选患者。符合条件的患者在移植前接受PBC，并在干预前后评估尿动力学参数。主要结果是膀胱容量的改善。次要结果包括排尿参数和围手术期泌尿系统并发症。结果：23例患者接受PBC治疗，时间最长为6个月。其中，20例（86%）患者达到目标膀胱容量≥250 ml。中位膀胱容量从PBC前的147.5 mL （IQR 128.8-155）显著增加到PBC后的265 mL (IQR 253.8-286.3) （p p p）结论：PBC是一种简单有效的门诊干预措施，可显著改善DB患者的膀胱容量和依从性，并可能减少肾移植期间和移植后可能发生的并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arab Journal of Urology UROLOGY & NEPHROLOGY-

CiteScore

2.80

自引率

0.00%

发文量

期刊介绍： The Arab Journal of Urology is a peer-reviewed journal that strives to provide a high standard of research and clinical material to the widest possible urological community worldwide. The journal encompasses all aspects of urology including: urological oncology, urological reconstructive surgery, urodynamics, female urology, pediatric urology, endourology, transplantation, erectile dysfunction, and urinary infections and inflammations. The journal provides reviews, original articles, editorials, surgical techniques, cases reports and correspondence. Urologists, oncologists, pathologists, radiologists and scientists are invited to submit their contributions to make the Arab Journal of Urology a viable international forum for the practical, timely and state-of-the-art clinical urology and basic urological research.