Mengjie Xiao , Tao Huang , Shengle Qin , Tianbo Zhang , Runfeng Li , Xin Zhao , Luping Lin , Zifeng Yang
{"title":"Anti-influenza formula medicines based on warm disease theory of traditional Chinese medicine","authors":"Mengjie Xiao , Tao Huang , Shengle Qin , Tianbo Zhang , Runfeng Li , Xin Zhao , Luping Lin , Zifeng Yang","doi":"10.1016/j.chmed.2026.02.008","DOIUrl":null,"url":null,"abstract":"<div><div>Warm disease, characterized primarily by fever, is caused by exogenous pathogenic factors, such as Influenza. Ancient medical books have documented treatment strategies, and many formulas and herbs have been identified as effective against influenza. Treatment on acute flu-induced pneumonia should consider suppressing viral replication and mitigating the tissue damage mediated by the immune system. Traditional Chinese medicines (TCMs) have superiority since their multi-ingredients and multi-targets. There are many formulas containing anti-influenza components and anti-inflammation components. TCM showed less resistance during application. Many formulas are common for clinic use like Lianhuaqingwen Capsule, Fufang Xiangru Liquid, and Shengjiang Powder. Their efficacy in viral elimination and inflammation regulation has been evaluated, leading to the identification of effective phytochemicals that elucidate their anti-flu mechanisms. This review introduces some Chinese patent medicines based on warm disease theory and reviews their current research process.</div></div>","PeriodicalId":9916,"journal":{"name":"Chinese Herbal Medicines","volume":"18 2","pages":"Pages 231-240"},"PeriodicalIF":11.2000,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chinese Herbal Medicines","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1674638426000109","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/2/10 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
Warm disease, characterized primarily by fever, is caused by exogenous pathogenic factors, such as Influenza. Ancient medical books have documented treatment strategies, and many formulas and herbs have been identified as effective against influenza. Treatment on acute flu-induced pneumonia should consider suppressing viral replication and mitigating the tissue damage mediated by the immune system. Traditional Chinese medicines (TCMs) have superiority since their multi-ingredients and multi-targets. There are many formulas containing anti-influenza components and anti-inflammation components. TCM showed less resistance during application. Many formulas are common for clinic use like Lianhuaqingwen Capsule, Fufang Xiangru Liquid, and Shengjiang Powder. Their efficacy in viral elimination and inflammation regulation has been evaluated, leading to the identification of effective phytochemicals that elucidate their anti-flu mechanisms. This review introduces some Chinese patent medicines based on warm disease theory and reviews their current research process.
期刊介绍:
Chinese Herbal Medicines is intended to disseminate the latest developments and research progress in traditional and herbal medical sciences to researchers, practitioners, academics and administrators worldwide in the field of traditional and herbal medicines. The journal's international coverage ensures that research and progress from all regions of the world are widely included.
CHM is a core journal of Chinese science and technology. The journal entered into the ESCI database in 2017, and then was included in PMC, Scopus and other important international search systems. In 2019, CHM was successfully selected for the “China Science and Technology Journal Excellence Action Plan” project, which has markedly improved its international influence and industry popularity. CHM obtained the first impact factor of 3.8 in Journal Citation Reports (JCR) in 2023.