Advances in Polymeric Drug Delivery Systems: From Biodegradability to Nanocarrier Technologies.

Abstract

Research studies indicate that biodegradable polymers play a crucial role in effective drug delivery, helping to manage drug release and decreasing potential toxic reactions. It thoroughly reviews different types of biodegradable polymers, the ways they are produced, and how they work for releasing drugs. The article begins by outlining drug-delivery polymers and then categorizes them into natural, synthetic, and biodegradable types. Eco-friendliness and biocompatibility are crucial attributes of degradable polymers, enhancing treatment outcomes significantly. The review covers the ways to develop and design biodegradable substances and how they are used in controlled-release medicines. The study delivers detailed descriptions of how controlled drugs are released through diffusion, degradation, and swelling. Different forms of polymer micelles, nanoparticles, dendrimers, and hydrogels are used to assess whether they can boost drug delivery methods. Polymeric nanocarriers improve targeting drugs, ensure their release over a long time, and enhance the solubility of some hydrophobic drugs. They are suitable for use in various types of therapy. The review points out that biodegradable polymers play a role in drug delivery for cancer and ocular disorders. This article aims to examine and evaluate biodegradable polymers, sharing their impacts on the development of controlled-release drug delivery technologies.