MEDICAL MANAGEMENT OF A LARGE NONRESTRICTIVE ATRIAL SEPTAL DEFECT IN A CRAB-EATING MACAQUE (MACACA FASCICULARIS).

IF 0.7 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Zoo and Wildlife Medicine Pub Date : 2026-03-01 DOI:10.1638/2025-0032

Antonin Boutibou, Norin Chai, Morgan Bureau, Valérie Chetboul

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引用次数: 0

Abstract

Atrial septal defects represent one of the most common congenital heart diseases in humans as well as in dogs and cats. However, reports in wildlife animals are limited. Additionally, ensuring treatment compliance and regular follow-ups in these species are often challenging. The aim of the present clinical brief is to describe the first successful long-term medical management of a nonrestrictive atrial septal defect in a crab-eating macaque (Macaca fascicularis). A seven-year-old castrated male crab-eating macaque was diagnosed with a severe left-to-right shunting, 7.5 mm atrial septal defect with altered general condition, right heart enlargement, and vena cava dilation. Medical treatment (spironolactone and taurine) was initiated and was associated with progressive improvement of the clinical status over time. Serial echocardiographic examinations confirmed substantial reduction of both defect size (0.9 mm) and right-sided volume overload. Two years after the initial diagnosis, the animal is doing well without any treatment.

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食蟹猕猴（束状猕猴）大房间隔非限制性缺损的医学处理。

房间隔缺损是人类以及狗和猫最常见的先天性心脏病之一。然而，关于野生动物的报道是有限的。此外，确保这些物种的治疗依从性和定期随访往往具有挑战性。本临床简报的目的是描述第一个成功的长期医疗管理的非限制性房间隔缺损的食蟹猕猴（Macaca束状猕猴）。一只7岁的雄性食蟹猕猴被阉割，诊断为严重的左向右分流，7.5 mm房间隔缺损，一般情况改变，右心增大，腔静脉扩张。开始进行药物治疗（螺内酯和牛磺酸），随着时间的推移，临床状况逐渐改善。连续超声心动图检查证实缺损尺寸（0.9 mm）和右侧容积超载均显著减小。在最初诊断两年后，这只动物在没有任何治疗的情况下恢复得很好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Zoo and Wildlife Medicine 农林科学-兽医学

CiteScore

1.70

自引率

14.30%

发文量

审稿时长

9-24 weeks

期刊介绍： The Journal of Zoo and Wildlife Medicine (JZWM) is considered one of the major sources of information on the biology and veterinary aspects in the field. It stems from the founding premise of AAZV to share zoo animal medicine experiences. The Journal evolved from the long history of members producing case reports and the increased publication of free-ranging wildlife papers. The Journal accepts manuscripts of original research findings, case reports in the field of veterinary medicine dealing with captive and free-ranging wild animals, brief communications regarding clinical or research observations that may warrant publication. It also publishes and encourages submission of relevant editorials, reviews, special reports, clinical challenges, abstracts of selected articles and book reviews. The Journal is published quarterly, is peer reviewed, is indexed by the major abstracting services, and is international in scope and distribution. Areas of interest include clinical medicine, surgery, anatomy, radiology, physiology, reproduction, nutrition, parasitology, microbiology, immunology, pathology (including infectious diseases and clinical pathology), toxicology, pharmacology, and epidemiology.