Transcriptomics analysis identifies folding and secretion related genes for improving monoclonal antibody production in Thermothelomyces heterothallica C1.

IF 4.9 2区生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Microbial Cell Factories Pub Date : 2026-04-02 DOI:10.1186/s12934-026-02989-w

Mari Mäkinen, Antti Aalto, Tiina Pakula, Marilyn G Wiebe, Anne Huuskonen, Marika Vitikainen, Mari Valkonen, Sami Havukainen, Ellinor Englund, Veera Korja, Mark Emalfarb, Noelia Valbuena Crespo, Ronen Tchelet, Markku Saloheimo

引用次数: 0

查看原文本刊更多论文

转录组学分析鉴定了改善异菌热thelomyces heterothallica C1单克隆抗体产生的折叠和分泌相关基因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Microbial Cell Factories 工程技术-生物工程与应用微生物

CiteScore

9.30

自引率

4.70%

发文量

235

审稿时长

2.3 months

期刊介绍： Microbial Cell Factories is an open access peer-reviewed journal that covers any topic related to the development, use and investigation of microbial cells as producers of recombinant proteins and natural products, or as catalyzers of biological transformations of industrial interest. Microbial Cell Factories is the world leading, primary research journal fully focusing on Applied Microbiology. The journal is divided into the following editorial sections: -Metabolic engineering -Synthetic biology -Whole-cell biocatalysis -Microbial regulations -Recombinant protein production/bioprocessing -Production of natural compounds -Systems biology of cell factories -Microbial production processes -Cell-free systems