Yu. M. Shlyapnikov, E. A. Malakhova, E. A. Shlyapnikova
{"title":"Ultrasensitive Biosensor Systems Based on Magnetic Nanomaterials for Monitoring Pathogens in the Environment","authors":"Yu. M. Shlyapnikov, E. A. Malakhova, E. A. Shlyapnikova","doi":"10.1134/S2635167625601330","DOIUrl":null,"url":null,"abstract":"<p>Iron oxide-based magnetic nanoparticles have found widespread application in bioanalytical methods. This review focuses on microarray-based analytical systems that employ micron-sized magnetic particles for signal detection. Their operation is determined by specific intermolecular recognition processes occurring in the surface layer on a scale of several nanometers, which allow these methods to be considered nanotechnological. Bioanalytical tests based on magnetic labels and microarrays are characterized by rapidity (analysis time up to 10 min), ultra-high sensitivity, and multiplexing capability. They are highly cost-effective and easy to implement, and thus hold great promise for solving problems of environmental pathogen monitoring that require a combination of high speed and sensitivity with the ability to automate analysis.</p>","PeriodicalId":716,"journal":{"name":"Nanotechnologies in Russia","volume":"20 1","pages":"S72 - S82"},"PeriodicalIF":0.8000,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nanotechnologies in Russia","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1134/S2635167625601330","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Engineering","Score":null,"Total":0}
引用次数: 0
Abstract
Iron oxide-based magnetic nanoparticles have found widespread application in bioanalytical methods. This review focuses on microarray-based analytical systems that employ micron-sized magnetic particles for signal detection. Their operation is determined by specific intermolecular recognition processes occurring in the surface layer on a scale of several nanometers, which allow these methods to be considered nanotechnological. Bioanalytical tests based on magnetic labels and microarrays are characterized by rapidity (analysis time up to 10 min), ultra-high sensitivity, and multiplexing capability. They are highly cost-effective and easy to implement, and thus hold great promise for solving problems of environmental pathogen monitoring that require a combination of high speed and sensitivity with the ability to automate analysis.
期刊介绍:
Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.