Ultrasensitive Biosensor Systems Based on Magnetic Nanomaterials for Monitoring Pathogens in the Environment

IF 0.8 Q3 Engineering
Yu. M. Shlyapnikov, E. A. Malakhova, E. A. Shlyapnikova
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引用次数: 0

Abstract

Iron oxide-based magnetic nanoparticles have found widespread application in bioanalytical methods. This review focuses on microarray-based analytical systems that employ micron-sized magnetic particles for signal detection. Their operation is determined by specific intermolecular recognition processes occurring in the surface layer on a scale of several nanometers, which allow these methods to be considered nanotechnological. Bioanalytical tests based on magnetic labels and microarrays are characterized by rapidity (analysis time up to 10 min), ultra-high sensitivity, and multiplexing capability. They are highly cost-effective and easy to implement, and thus hold great promise for solving problems of environmental pathogen monitoring that require a combination of high speed and sensitivity with the ability to automate analysis.

基于磁性纳米材料的超灵敏生物传感器系统监测环境中的病原体
氧化铁基磁性纳米颗粒在生物分析方法中得到了广泛的应用。这篇综述的重点是基于微阵列的分析系统,采用微米大小的磁性颗粒进行信号检测。它们的操作是由发生在几纳米尺度的表层的特定分子间识别过程决定的,这使得这些方法被认为是纳米技术。基于磁标记和微阵列的生物分析测试具有快速(分析时间长达10分钟),超高灵敏度和多路复用能力的特点。它们具有很高的成本效益和易于实施,因此在解决需要高速、灵敏度和自动化分析能力相结合的环境病原体监测问题方面具有很大的希望。
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来源期刊
Nanotechnologies in Russia
Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍: Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.
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