{"title":"Steady progress in the treatment of advanced prostate cancer: a year in review.","authors":"Theodore Gourdin","doi":"10.1097/CCO.0000000000001237","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>This review is designed to highlight recent research efforts to optimize treatment strategies in men with advanced prostate cancer.</p><p><strong>Recent findings: </strong>In hopes of improving outcomes in men with advanced prostate cancer, recent trials have focused on intensifying therapy earlier in the disease course both in men with biochemical recurrence and those with oligometastatic disease. Further research efforts have looked to refine the use of radiopharmaceuticals, targeted therapy, and combinations of existing agents. Finally, systemic therapies with novel targets may expand options for men with treatment-refractory metastatic castration-resistant disease.</p><p><strong>Summary: </strong>Ongoing research focuses on maximizing the benefits of existing therapies while exploring treatments with new mechanisms of action.</p>","PeriodicalId":10893,"journal":{"name":"Current Opinion in Oncology","volume":"38 3","pages":"243-248"},"PeriodicalIF":2.4000,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Oncology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/CCO.0000000000001237","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/4/2 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: This review is designed to highlight recent research efforts to optimize treatment strategies in men with advanced prostate cancer.
Recent findings: In hopes of improving outcomes in men with advanced prostate cancer, recent trials have focused on intensifying therapy earlier in the disease course both in men with biochemical recurrence and those with oligometastatic disease. Further research efforts have looked to refine the use of radiopharmaceuticals, targeted therapy, and combinations of existing agents. Finally, systemic therapies with novel targets may expand options for men with treatment-refractory metastatic castration-resistant disease.
Summary: Ongoing research focuses on maximizing the benefits of existing therapies while exploring treatments with new mechanisms of action.
期刊介绍：
With its easy-to-digest reviews on important advances in world literature, Current Opinion in Oncology offers expert evaluation on a wide range of topics from sixteen key disciplines including sarcomas, cancer biology, melanoma and endocrine tumors. Published bimonthly, each issue covers in detail the most pertinent advances in these fields from the previous year. This is supplemented by annotated references detailing the merits of the most important papers.
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