M. P. Ryndyk, I. E. Nifant’ev, A. N. Tavtorkin, P. V. Ivchenko
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引用次数: 0
Abstract
In recent years, there has been a sustainable advancement of regenerative medicine, including the development of tissue-engineered constructs and their implementation in clinical practice. Current tissue engineering methods and approaches actively use biodegradable materials, among them of protein origin. Silk fibroin, which exhibits superior physicomechanical properties compared to other proteins, holds great high potential for use in this area. To enhance functionality and biocompatibility, silk fibroin can be modified with bioactive additives such as collagen, gelatin, hydroxyapatite, physiologically significant compounds, and drugs. This review addresses methods for the isolation and properties of silk fibroin, analyzes the characteristics of composites containing silk fibroin, and highlights the latest achievements and prospects for the application of silk fibroin-based materials in regenerative medicine.
期刊介绍：
Polymer Science, Series C (Selected Topics) is a journal published in collaboration with the Russian Academy of Sciences. Series C (Selected Topics) includes experimental and theoretical papers and reviews on the selected actual topics of macromolecular science chosen by the editorial board (1 issue a year). Submission is possible by invitation only. All journal series present original papers and reviews covering all fundamental aspects of macromolecular science. Contributions should be of marked novelty and interest for a broad readership. Articles may be written in English or Russian regardless of country and nationality of authors. All manuscripts are peer reviewed
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