A Numerical Approach to Brace Treatment Prediction by Comprehensive Biomechanical Modeling of Adolescent Idiopathic Scoliosis

IF 2.1 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Ali Bakhshian Talkhoncheh, Borhan Beigzadeh
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引用次数: 0

Abstract

Adolescent idiopathic scoliosis (AIS) requires effective and personalized brace treatment strategies to prevent progression and the potential need for surgery. However, monitoring and prediction of the spinal column deformities during bracing is not always possible. Relying only on traditional methods or clinicians' experience may pose a complex challenge in orthopedic care, as unique biological characteristics of each patient make it difficult to decide on the optimal spinal brace treatment. This study introduces a comprehensive biomechanical modeling approach utilizing finite element analysis and neural networks to refine brace prescription and treatment outcomes. The Rigo Chêneau-type brace, known for its biomechanical principles targeting lateral displacement and transversal derotation, serves as the foundation for this study. A dataset of 120 diverse abnormal curvatures is analyzed to estimate the effectiveness of the proposed biomechanical brace mechanism prior to its design and fabrication. Through 3600 simulations across various curvature types and severity levels, the study evaluated brace performance in terms of coronal correction, sagittal plane stability, and stress distribution. Simulation findings indicate significant improvements in coronal alignment between 10% and 50% while preserving the physiological sagittal curves. Subsequently, simulation data were utilized for training a neural network model to estimate the spinal column position after using the prescribed brace. The trained scoliosis model demonstrated 90.6% accuracy in predicting spinal deviation changes. By leveraging advanced computational tools and patient-specific biomechanical data, the current simulations offer a promising approach for optimizing brace treatment in AIS patients by predicting the outcomes.

基于综合生物力学模型的青少年特发性脊柱侧凸支架治疗预测的数值方法。
青少年特发性脊柱侧凸(AIS)需要有效和个性化的支架治疗策略,以防止进展和潜在的手术需求。然而,监测和预测支撑期间脊柱畸形并不总是可能的。仅依靠传统方法或临床医生的经验可能会给骨科护理带来复杂的挑战,因为每个患者独特的生物学特性使得难以确定最佳的脊柱支架治疗方法。本研究引入了一种综合的生物力学建模方法,利用有限元分析和神经网络来优化支具处方和治疗结果。Rigo Chêneau-type支具以其针对横向位移和横向旋转的生物力学原理而闻名,是本研究的基础。在设计和制造之前,对120种不同异常曲率的数据集进行了分析,以估计所提出的生物力学支撑机构的有效性。通过各种曲率类型和严重程度的3600次模拟,该研究评估了支具在冠状面矫正、矢状面稳定性和应力分布方面的性能。模拟结果表明,在保留生理矢状曲线的同时,冠状线的显着改善在10%到50%之间。随后,利用仿真数据训练神经网络模型来估计使用规定支架后脊柱的位置。训练后的脊柱侧凸模型预测脊柱偏差变化的准确率为90.6%。通过利用先进的计算工具和患者特定的生物力学数据,目前的模拟为通过预测结果来优化AIS患者的支具治疗提供了一种很有前途的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
International Journal for Numerical Methods in Biomedical Engineering
International Journal for Numerical Methods in Biomedical Engineering ENGINEERING, BIOMEDICAL-MATHEMATICAL & COMPUTATIONAL BIOLOGY
CiteScore
4.50
自引率
9.50%
发文量
103
审稿时长
3 months
期刊介绍: All differential equation based models for biomedical applications and their novel solutions (using either established numerical methods such as finite difference, finite element and finite volume methods or new numerical methods) are within the scope of this journal. Manuscripts with experimental and analytical themes are also welcome if a component of the paper deals with numerical methods. Special cases that may not involve differential equations such as image processing, meshing and artificial intelligence are within the scope. Any research that is broadly linked to the wellbeing of the human body, either directly or indirectly, is also within the scope of this journal.
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