EPIDEMIOLOGY, DIAGNOSIS, MANAGEMENT AND PREVENTION OF STROKE: A NARRATIVE REVIEW.

I A Azeez, O A Oguniyi, O J Osarenkhoe, A K Adeyemo, A Adetona, A J Lasis, Y A Aderibigbe, H K Alade, O O Oyelayo, A B Abdulraheem, R D Agbana
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Abstract

Introduction: Stroke is a major public health problem globally, and surviving patients have very high risks of recurrence. Age, sex, ethnicity, transient ischaemic attack(TIA), and hereditary characteristics are non-modifiable risk factors while the major modifiable risk factors for stroke are hypertension, diabetes, lack of physical exercise, alcohol and drug abuse, cholesterol, diet management and cardiac diseases.

Objective: The aim of this narrative review was to discuss the current management and prevention of stroke.

Methods: In this review, the databases of Medline (PubMed), Scopus, Web of Science and Google Scholar were used for literature search. The MESH terms used included "Diagnosis of Stroke", "Epidemiology of Stroke", "Management of Stroke" and "Prevention of Stroke". The other terms were "Stroke Mimicks" and "Biomarkers of Stroke". Studies that evaluated the current management of stroke in adult patients were included. This article is guided by the Scale for the Assessment of Narrative Review Articles (SANRA).

Results: A total of 800 studies were found. After excluding duplicate papers and applying the inclusion and exclusion criteria, 72 studies were included for review. The included studies were published between 2010 and 2025. These studies included 9 Randomised Controlled Ttrials, a cohort study and other studies.

Conclusion: Computed tomography (CT) scan of the brain is the most common form of clinical imaging procedure used in the treatment of stroke and Non-contrast CT Scans are usually the first step in imaging process. Diffusion-weighted magnetic resonance imaging (MRI) is the most sensitive imaging technique, it shows ischaemic changes very early and is effective in the evaluation of cerebral changes in ischaemic stroke. Magnetic resonance imaging is more precise in excluding intracranial hemorrhage and MRI with DWI is more accurate in the revealing acute ischemic stroke. Stroke treatment mainly focuses on restoring blood flow to the brain and treating stroke-induced neurological injury.

脑卒中的流行病学、诊断、管理和预防:叙述性综述。
脑卒中是全球性的重大公共卫生问题,存活患者的复发风险非常高。年龄、性别、种族、短暂性脑缺血发作(TIA)和遗传特征是不可改变的危险因素,而中风的主要可改变的危险因素是高血压、糖尿病、缺乏体育锻炼、酗酒和滥用药物、胆固醇、饮食管理和心脏病。目的:这篇叙述性综述的目的是讨论当前脑卒中的管理和预防。方法:采用Medline (PubMed)、Scopus、Web of Science、谷歌Scholar等数据库进行文献检索。使用的MESH术语包括“中风诊断”、“中风流行病学”、“中风管理”和“中风预防”。其他术语是“中风模拟物”和“中风生物标志物”。评估当前成年卒中患者管理的研究被纳入。本文以叙述性评论文章评估量表(SANRA)为指导。结果:共发现800项研究。在排除重复论文并应用纳入和排除标准后,纳入了72项研究。纳入的研究发表于2010年至2025年之间。这些研究包括9项随机对照试验、一项队列研究和其他研究。结论:计算机断层扫描(CT)是脑卒中治疗中最常用的临床成像程序,而非对比CT扫描通常是成像过程的第一步。磁共振弥散加权成像(diffusion weighted magnetic resonance imaging, MRI)是最灵敏的成像技术,它能很早地显示缺血改变,是评估缺血性脑卒中大脑变化的有效方法。磁共振成像在排除颅内出血方面更精确,MRI加DWI在揭示急性缺血性脑卒中方面更准确。脑卒中的治疗主要集中在恢复脑血流量和治疗脑卒中引起的神经损伤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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