Squamous cell carcinoma in a captive Sunda pangolin (Manis javanica): clinical management and pathological findings.

IF 1.1 4区 农林科学 Q3 VETERINARY SCIENCES
Journal of Veterinary Medical Science Pub Date : 2026-05-01 Epub Date: 2026-03-24 DOI:10.1292/jvms.25-0504
Shin Min Chong, Charlene Yen-Feng Yeong, Ali Anwar Ahmad, Yirui Heng
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引用次数: 0

Abstract

An adult male Sunda pangolin (Manis javanica) exhibited thickened, hyperkeratotic skin between dorsal scales. Initial wound management led to temporary resolution, but a proliferative, hemorrhagic mass developed 11 weeks later. Histopathological examination confirmed squamous cell carcinoma (SCC). Surgical excision followed by cryotherapy was performed. Despite histological evidence of complete tumor ablation, the animal's condition deteriorated due to secondary infection and poor wound healing. This case highlights the diagnostic and therapeutic challenges of managing SCC in pangolins due to their unique integumentary anatomy. This is the first documented case of cutaneous SCC in a Sunda pangolin and expands the known disease spectrum in this critically endangered species.

圈养巽他穿山甲鳞状细胞癌:临床处理和病理结果。
一只成年雄性巽他穿山甲(Manis javanica)在背部鳞片之间表现出增厚、角化过度的皮肤。最初的伤口处理导致了暂时的解决,但11周后出现了增殖性出血肿块。组织病理学检查证实为鳞状细胞癌。手术切除后进行冷冻治疗。尽管组织学证据表明肿瘤完全消融,但由于继发性感染和伤口愈合不良,动物的病情恶化。由于穿山甲独特的表皮解剖结构,本病例突出了诊断和治疗管理鳞状细胞癌的挑战。这是在巽他穿山甲中发现的首例皮肤鳞状细胞癌病例,扩大了这种极度濒危物种的已知疾病范围。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Veterinary Medical Science
Journal of Veterinary Medical Science 农林科学-兽医学
CiteScore
2.30
自引率
8.30%
发文量
230
审稿时长
9-18 weeks
期刊介绍: JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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